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磷酸化沉默调节蛋白1抗体 田源一抗磷酸化抗体
点击次数:140发布时间:2012/8/14 10:17:33
更新日期:2013/6/26 15:47:47
所 在 地:其它
产品型号:Anti-Phospho-SirT1 (Ser27)
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详细内容
磷酸化沉默调节蛋白1抗体Anti-Phospho-SirT1 (Ser27)hSIR2; hSIRT1; NAD dependent deacetylase SIRT1; NAD dependent deacetylase sirtuin 1; NAD d
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性能参数:
中文名称:磷酸化沉默调节蛋白1抗体
英文名称:Anti-Phospho-SirT1 (Ser27)
别名:hSIR2; hSIRT1; NAD dependent deacetylase SIRT1; NAD dependent deacetylase sirtuin 1; NAD d
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. Subcellular Location : SirtT1 75 kDa fragment: Cytoplasm. Mitochondrion.Tissue Specificity : Widely expressed.Similarity : Belongs to the sirtuin family. Contains 1 deacetylase sirtuin-type domain.Subunit : Found in a complex with PCAF and MYOD1.在Sirtuin蛋白家族中,sirtuin 1参与多种新陈代谢活动,包括DNA的自我保护和修复,抑制脂质过氧化积累,抑制其他细胞凋亡相关基因的表达以及和细胞寿命相关的活动。限制摄入的热量可以加强SIRT1的表达,从而延长了寿命。磷酸化沉默调节蛋白1抗体的质量标准:
■其它名称: | hSIR2; hSIRT1; NAD dependent deacetylase SIRT1; NAD dependent deacetylase sirtuin 1; NAD d |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/神经生物学/信号转导/细胞凋亡/表观遗传学 |
■蛋白分子: | predicted molecular weight: 82kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human SirT1 around the phosphorylation site of Ser27 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化沉默调节蛋白1抗体Anti-Phospho-SirT1 (Ser27)的相关产品目录:
1mg/1ml 磷酸化沉默调节蛋白1抗体 Anti-Phospho-SirT1 (Ser27) hSIR2; hSIRT1; NAD dependent deacetylase SIRT1; NAD dependent deacetylase sirtuin 1; NAD d的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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