产品展示
血影蛋白/收缩蛋白抗体 田源一抗
点击次数:192发布时间:2012/8/14 10:17:36
更新日期:2013/6/26 15:47:47
所 在 地:其它
产品型号:Anti-alpha 1 Spectrin/Spectrin α
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详细内容
血影蛋白/收缩蛋白抗体Anti-alpha 1 Spectrin/Spectrin αSpectrin-Alpha; SPEC;Spectrin-α; Spectrin, alpha, non-erythrocy tic 1 variant; Spna 2 prot
360TIYO.COM-上海田源公司
性能参数:
中文名称:血影蛋白/收缩蛋白抗体
英文名称:Anti-alpha 1 Spectrin/Spectrin α
别名:Spectrin-Alpha; SPEC;Spectrin-α; Spectrin, alpha, non-erythrocy tic 1 variant; Spna 2 prot
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type2, pyropoikilocytosis, and spherocytic hemolytic anemia.Subcellular Location : Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.Similarity : Belongs to the spectrin family.Contains 3 EF-hand domains.Contains 1 SH3 domain.Contains 23 spectrin repeats.Subunit : Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts with isoform 1 of ACP1. Interacts with CALM and EMD. Interacts (via C-terminal spectrin repeats) with TRPC4. Identified in a complex with ACTN4, CASK, IQGAP1, MAGI2, NPHS1 and SPTBN1.血影蛋白(spectrin)又称收缩蛋白,是红细胞膜骨架的主要成份,参与了细胞骨架结构的形成。但不是红细胞膜蛋白的成份,约占膜提取蛋白的30%。血影蛋白属是类似肌球蛋白的膜的外在性蛋白的一种。Spectrin α是膜里侧结构蛋白质,除起支持双层脂质外,还有保持红细胞外形的作用,Spectrin-α占里侧结构蛋白之60—70%。血影蛋白/收缩蛋白抗体的质量标准:
■其它名称: | Spectrin-Alpha; SPEC;Spectrin-α; Spectrin, alpha, non-erythrocy tic 1 variant; Spna 2 prot |
■交叉反应: | hu, mo, rat, dog, cow |
■产品类型: | 一抗 |
■应用领域: | /心血管/细胞生物 |
■蛋白分子: | predicted molecular weight: 279kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Spectrin-Alpha (20-65aa) |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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血影蛋白/收缩蛋白抗体Anti-alpha 1 Spectrin/Spectrin α的相关产品目录:
1mg/1ml 血影蛋白/收缩蛋白抗体 Anti-alpha 1 Spectrin/Spectrin α Spectrin-Alpha; SPEC;Spectrin-α; Spectrin, alpha, non-erythrocy tic 1 variant; Spna 2 prot的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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