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磷酸化细胞信号转导分子SMAD3抗体 田源一抗磷酸化抗体
点击次数:144发布时间:2012/8/14 10:18:41
更新日期:2013/6/26 15:46:40
所 在 地:其它
产品型号:Anti-Phospho-Smad3(Ser425)
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详细内容
磷酸化细胞信号转导分子SMAD3抗体Anti-Phospho-Smad3(Ser425)SMAD3(phospho S425); hMAD 3; hSMAD3; HSPC193; JV15 2; JV152; MAD (mothers against decapent
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化细胞信号转导分子SMAD3抗体
英文名称:Anti-Phospho-Smad3(Ser425)
别名:SMAD3(phospho S425); hMAD 3; hSMAD3; HSPC193; JV15 2; JV152; MAD (mothers against decapent
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.磷酸化细胞信号转导分子SMAD3抗体的质量标准:
■其它名称: | SMAD3(phospho S425); hMAD 3; hSMAD3; HSPC193; JV15 2; JV152; MAD (mothers against decapent |
■交叉反应: | hu, mo, rat, hrs, cow, pig, chk, Rb |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/免疫学/信号转导/细胞凋亡/转录调节因子 |
■蛋白分子: | predicted molecular weight: 47kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human Smad3 around the phosphorylation site of Ser425 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化细胞信号转导分子SMAD3抗体Anti-Phospho-Smad3(Ser425)的相关产品目录:
1mg/1ml 磷酸化细胞信号转导分子SMAD3抗体 Anti-Phospho-Smad3(Ser425) SMAD3(phospho S425); hMAD 3; hSMAD3; HSPC193; JV15 2; JV152; MAD (mothers against decapent的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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