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磷酸化转化生长因子β活化激酶结合蛋白1抗体 田源一抗
点击次数:134发布时间:2012/8/14 10:20:02
更新日期:2013/6/26 15:46:24
所 在 地:其它
产品型号:Anti-phospho-MAP3K7IP1(Ser423)
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详细内容
磷酸化转化生长因子β活化激酶结合蛋白1抗体Anti-phospho-MAP3K7IP1(Ser423)MAP3K7IP1(phospho S423); MAP3K7IP 1; MAP3K7IP1; Mitogen activated protein kinase kinase ki
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性能参数:
中文名称:磷酸化转化生长因子β活化激酶结合蛋白1抗体
英文名称:Anti-phospho-MAP3K7IP1(Ser423)
别名:MAP3K7IP1(phospho S423); MAP3K7IP 1; MAP3K7IP1; Mitogen activated protein kinase kinase ki
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.磷酸化转化生长因子β活化激酶结合蛋白1抗体的质量标准:
■其它名称: | MAP3K7IP1(phospho S423); MAP3K7IP 1; MAP3K7IP1; Mitogen activated protein kinase kinase ki |
■交叉反应: | hu, mo, rat |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/免疫学/信号转导/转录调节因子/激酶和磷酸酶 |
■蛋白分子: | predicted molecular weight: 55-60kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human MAP3K7IP1 around the phosphorylation site of Ser423 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化转化生长因子β活化激酶结合蛋白1抗体Anti-phospho-MAP3K7IP1(Ser423)的相关产品目录:
1mg/1ml 磷酸化转化生长因子β活化激酶结合蛋白1抗体 Anti-phospho-MAP3K7IP1(Ser423) MAP3K7IP1(phospho S423); MAP3K7IP 1; MAP3K7IP1; Mitogen activated protein kinase kinase ki的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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