磷酸化NF-κB活化激酶抗体Anti-Phospho-TBK1/NAK （Ser172）TRAF-associated NF-κB kinase; TANK protein; TANK-binding kinase 1; T2K; NF-kappa-B-activat
360TIYO.COM-上海田源公司

性能参数：

中文名称：磷酸化NF-κB活化激酶抗体
英文名称：Anti-Phospho-TBK1/NAK （Ser172）
别名：TRAF-associated NF-κB kinase; TANK protein; TANK-binding kinase 1; T2K; NF-kappa-B-activat
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

产品详细描述

产品介绍：Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 ａnd interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates Borna disease virus （BDV） P protein. Phosphorylates ａnd activates IRF3 ａnd IRF7 ａnd allows their nuclear localization. This leads to production of alpha/beta interferons ａnd the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response. Inhibition of its interaction with IRF3, due to HCV NS3 binding or BDV P protein seems to be one mechanism of inhibition of the innate immune responses of hepatitis C virus （HCV） infection or Borna disease virus infection respectively. Ubiquitous with higher expression in testis. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.Subcellular Location : Cytoplasm.Tissue Specificity : Ubiquitous with higher expression in testis.Similarity : Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. Contains 1 protein kinase domain. Contains 1 ubiquitin-like domain.Subunit : Self-associates. Interacts with TIRAP, TANK ａnd TRAF2. Part of a ternary complex consisting of TANK, TRAF2 ａnd TBK1.TBK1是NF-κB信号通道中的一种激酶，它是被KRAS-改变的细胞存活所必不可少的。TBK1诱导反凋亡信号，TBK1与NF-κB共同作用于KRAS介导的癌变过程中,可能是一个癌症治疗目标。

磷酸化NF-κB活化激酶抗体的质量标准：

■其它名称：	TRAF-associated NF-κB kinase; TANK protein; TANK-binding kinase 1; T2K; NF-kappa-B-activat
■交叉反应：	hu, mo, rat, chk, hrs, cow, dog, Rb
■产品类型：	一抗磷酸化抗体
■应用领域:	/肿瘤/免疫学/信号转导/细胞凋亡/转录调节因子/激酶和磷酸酶
■蛋白分子：	predicted molecular weight: 55kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated Synthesised phosphopeptide derived from human TBK1 around the phosphorylation site of Ser172
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－－

质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
4、田源将联系客户并提供质量投诉处理结果。

友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

磷酸化NF-κB活化激酶抗体Anti-Phospho-TBK1/NAK （Ser172）的相关产品目录：







1mg/1ml 磷酸化NF-κB活化激酶抗体 Anti-Phospho-TBK1/NAK （Ser172） TRAF-associated NF-κB kinase; TANK protein; TANK-binding kinase 1; T2K; NF-kappa-B-activat的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

上海田源专业销售磷酸化NF-κB活化激酶抗体 Anti-Phospho-TBK1/NAK （Ser172），了解更多请点击查询！