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端粒酶相关蛋白1抗体 田源一抗
点击次数:193发布时间:2012/8/14 10:21:29
更新日期:2013/6/26 15:46:18
所 在 地:其它
产品型号:Anti-TEP1
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详细内容
端粒酶相关蛋白1抗体Anti-TEP1Telomerase Associated pratein-1; TEP1; TLP1; TP1 TP-1; Telomerase protein component 1; Tel
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性能参数:
中文名称:端粒酶相关蛋白1抗体
英文名称:Anti-TEP1
别名:Telomerase Associated pratein-1; TEP1; TLP1; TP1 TP-1; Telomerase protein component 1; Tel
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TEP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TEP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.Subcellular Location : Nucleus (Probable). Telomere.Tissue Specificity : Ubiquitous.Subunit : Component of the telomerase holoenzyme complex at least composed of TERT, DKC1, WRAP53/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and a telomerase RNA template component (TERC).端粒酶相关蛋白1抗体的质量标准:
■其它名称: | Telomerase Associated pratein-1; TEP1; TLP1; TP1 TP-1; Telomerase protein component 1; Tel |
■交叉反应: | hu, mo, rat, dog, pig, cow, chk |
■产品类型: | 一抗 |
■应用领域: | /神经生物学/信号转导 |
■蛋白分子: | predicted molecular weight: 289kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human TP-1 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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端粒酶相关蛋白1抗体Anti-TEP1的相关产品目录:
1mg/1ml 端粒酶相关蛋白1抗体 Anti-TEP1 Telomerase Associated pratein-1; TEP1; TLP1; TP1 TP-1; Telomerase protein component 1; Tel的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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