泛素蛋白抗体Anti-Ubiquitin/UBC/UBFLJ25987; MGC8385; Polyubiquitin B; UBB; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; U
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性能参数：

中文名称：泛素蛋白抗体
英文名称：Anti-Ubiquitin/UBC/UB
别名：FLJ25987; MGC8385; Polyubiquitin B; UBB; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; U
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Ubiquitin is a highly conserved protein, which has an ATP dependent role in the targeting of proteins for proteolytic degradation. To perform this function, the protein to be degraded is first covalently attached to the C terminus of ubiquitin, ａnd the ubiquitinated complex is then recognized by a complex of degradative enzymes. Interestingly, ubiquitin also becomes covalently bonded to many types of pathological inclusions, which appear to be resistant to normal degradation. Therefore, ubiquitin antibodies are very useful for studies of these inclusions. For example, the neurofibrillary tangles ａnd paired helical filaments diagnostic of Alzheimer＇s disease, Lewy bodies seen in Parkinson＇s disease, ａnd Pick bodies found in Pick＇s disease are all heavily ubiquitinated ａnd can be readily visualized with ubiquitin antibodies.Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation ａnd may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis ａnd DNA repair.Subcellular Location : Cell Membrane, Cytoplasmic ａnd Nuclear泛素及类泛素蛋白（Ubls） 存在在多种细胞中，有多种细胞调控的功能，如细胞增殖、凋亡、细胞周期及DNA修复等。 但泛素途径的异常会导致人类疾病的产生，包括多种形式的肿瘤的发生，神经退变等都与泛素有关。

泛素蛋白抗体的质量标准：

■其它名称：	FLJ25987; MGC8385; Polyubiquitin B; UBB; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; U
■交叉反应：	mo, rat, hu, pig
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/神经生物学/细胞凋亡/泛素
■蛋白分子：	predicted molecular weight: 8.5/17/34/75kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Ubiquitin C-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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质量投诉流程
1、向我们的客户服务部反应投诉原因及订单信息。
2、向我们发送投诉相关的证明材料。
3、田源时间进行质量投诉调查及处理调查结果。
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友情提醒：
部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
1、超过质量投诉期的进口产品投诉
2、非质量报告提及的指标投诉

泛素蛋白抗体Anti-Ubiquitin/UBC/UB的相关产品目录：







1mg/1ml 泛素蛋白抗体 Anti-Ubiquitin/UBC/UB FLJ25987; MGC8385; Polyubiquitin B; UBB; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; U的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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