L-型电压依赖型钙通道α抗体Anti-VDCC-L alpha/CCHL1A1VDCC-L alpha 1; L-VDCC alpha 1; Voltage dependent calcium channel subunit alpha 1; CACNL1A
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性能参数：

中文名称：L-型电压依赖型钙通道α抗体
英文名称：Anti-VDCC-L alpha/CCHL1A1
别名：VDCC-L alpha 1; L-VDCC alpha 1; Voltage dependent calcium channel subunit alpha 1; CACNL1A
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments ａnd forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, ａnd gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to ａnd is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]Subcellular Location : Membrane; Multi-pass membrane protein. Cell membrane. Note=The interaction between RRAD ａnd CACNB2 regulates its trafficking to the cell membrane.Tissue Specificity : Expressed in brain, heart, jejunum, ovary, pancreatic beta-cells ａnd vascular smooth muscle. Overall expression is reduced in atherosclerotic vascular smooth muscle.Similarity : Belongs to the calcium channel alpha-1 subunit （TC 1.A.1.11） family. CACNA1C subfamily.Subunit : Voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta ａnd delta subunits in a 1:1:1:1 ratio. L型钙通道广泛分布于心肌细胞膜上，尤其T管上含量*为丰富，是心肌细胞膜的主要钙通道类型。L型钙通道的开闭主要受膜电位变化的影响，是电压依赖性钙通道，激活电位-40～-30mV，失活电位-20mV。L型钙通道开放后持续的时间长较长，激活占时20～30ms，失活更慢（100～300ms），又称为慢钙通道。

L-型电压依赖型钙通道α抗体的质量标准：

■其它名称：	VDCC-L alpha 1; L-VDCC alpha 1; Voltage dependent calcium channel subunit alpha 1; CACNL1A
■交叉反应：	hu, mo, rat, Rb, dog, pig, cow, hrs
■产品类型：	一抗
■应用领域:	/心血管/免疫学/神经生物学/通道蛋白
■蛋白分子：	predicted molecular weight: 238kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human VDCC-L alpha
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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部分进口产品投诉须按照进口产品要求的检测方法提供证据。
由于化学产品的特殊性，恕不接受以下投诉：
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L-型电压依赖型钙通道α抗体Anti-VDCC-L alpha/CCHL1A1的相关产品目录：







1mg/1ml L-型电压依赖型钙通道α抗体 Anti-VDCC-L alpha/CCHL1A1 VDCC-L alpha 1; L-VDCC alpha 1; Voltage dependent calcium channel subunit alpha 1; CACNL1A的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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