磷酸化血管内皮生长因子受体2抗体Anti-phospho-VEGFR2（Tyr951）VEGFR2（Phospho-Tyr951）; CD309 antigen; Fetal liver kinase 1; FLK1; KDR; Kinase ｉnsert doma
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性能参数：

中文名称：磷酸化血管内皮生长因子受体2抗体
英文名称：Anti-phospho-VEGFR2（Tyr951）
别名：VEGFR2（Phospho-Tyr951）; CD309 antigen; Fetal liver kinase 1; FLK1; KDR; Kinase ｉnsert doma
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：Hemangioblast MarkerVEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration ａnd differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises ａnd is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 ａnd phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 ａnd 1059 in the activation loop is required for activation of VEGF receptor 2 ａnd its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi＇s sarcoma lesions.Subcellular Location : Isoform 1: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Isoform 2: Secreted. Isoform 3: Secreted.Tissue Specificity : Detected in cornea （at protein level）. Widely expressed.Similarity : Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.Contains 7 Ig-like C2-type （immunoglobulin-like） domains.Contains 1 protein kinase domain.Subunit : Interacts with MYOF （By similarity）. Interacts with VEGFA, VEGFC ａnd VEGFD. Monomer in the absence of bound VEGFA, VEGFC or VEGFD. Homodimer in the presence of bound dimeric VEGFA, VEGFC or VEGFD. Can also form heterodimers with FLT1 ａnd FLT4. Interacts （tyrosine phosphorylated） with FYN, NCK1, PLCG1 ａnd SHB. Interacts with HIV-1 Tat. Interacts with CBL. Interacts with SH2D2A/TSAD ａnd GRB2.细胞膜受体（Membrane Receptors） 成血管细胞标志物 VEGFR-2是一种细胞膜受体激酶，对血管内皮生长因子-VEGF有高度的亲和性，主要功能是参与血管内皮细胞生长和血管生成的调控,参与血管内皮细胞的生长。用于各种恶性肿瘤的研究。

磷酸化血管内皮生长因子受体2抗体的质量标准：

■其它名称：	VEGFR2（Phospho-Tyr951）; CD309 antigen; Fetal liver kinase 1; FLK1; KDR; Kinase ｉnsert doma
■交叉反应：	hu, mo, rat, Rb
■产品类型：	一抗磷酸化抗体
■应用领域:	/心血管/细胞生物/免疫学/神经生物学/生长因子和激素
■蛋白分子：	predicted molecular weight: 26kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH cunjugated Synthetic phosphopeptide derived from human VEGFR2 around the phosphorylation site of Tyr951
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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磷酸化血管内皮生长因子受体2抗体Anti-phospho-VEGFR2（Tyr951）的相关产品目录：







1mg/1ml 磷酸化血管内皮生长因子受体2抗体 Anti-phospho-VEGFR2（Tyr951） VEGFR2（Phospho-Tyr951）; CD309 antigen; Fetal liver kinase 1; FLK1; KDR; Kinase ｉnsert doma的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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