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囊泡相关膜蛋白2抗体 田源一抗
点击次数:189发布时间:2012/8/15 9:15:48
更新日期:2013/6/26 15:27:48
所 在 地:其它
产品型号:Anti-VAMP-2
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详细内容
囊泡相关膜蛋白2抗体Anti-VAMP-2Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobr
360TIYO.COM-上海田源公司
性能参数:
中文名称:囊泡相关膜蛋白2抗体
英文名称:Anti-VAMP-2
别名:Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobr
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:VAMP2 (Synaptobrevin 2) is a small integral membrane protein found specifically in synaptic vesicles in neurons. Synaptobrevins/VAMPs, syntaxins, and the 25 kD synaptosomal associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP2 is one of a family of integral membrane proteins of 11-13 kDa with the N terminal region exposed to the cytoplasm and a C terminal transmembrane domain. Two isoforms identified in the mammalian CNS Synaptobrevin 1/VAMP 1 and Synaptobrevin 2/VAMP 2 differ in their distribution within different brain regions. Synaptobrevin/VAMP is highly conserved between vertebrates and invertebrates. It is a major constituent of synaptic vesicles and peptidergic secretory granules in all neurons examined so far. In addition, it is present on secretory granules of neuroendocrine cells. Low levels of synaptobrevin 2/VAMP 2 are present in many other tissues where the protein resides on specialized microvesicles. In non-neuronal cells, the third isoform, Cellubrevin/VAMP 3, is present where it is localized to an endosomal membrane pool. Synaptobrevin/VAMP is an essential component of the exocytotic fusion machine, related to a larger protein family referred to as v SNAREs. It is the sole target for tetanus and several of the botulinal neurotoxins which cleave the protein at single sites in the C terminal portion of the molecule.VAMP-2是真核生物中的一种膜受体蛋白,该蛋白在真核生物的胞吐、信号传导、胞内运输和分泌等活动中起到重要作用.囊泡相关膜蛋白2抗体的质量标准:
■其它名称: | Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobr |
■交叉反应: | hu, mo, rat, hrs, cow, pig, dog, Gpig, Rb, chk |
■产品类型: | 一抗 |
■应用领域: | /肿瘤/神经生物学/信号转导 |
■蛋白分子: | predicted molecular weight: 13kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human VAMP-2 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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囊泡相关膜蛋白2抗体Anti-VAMP-2的相关产品目录:
1mg/1ml 囊泡相关膜蛋白2抗体 Anti-VAMP-2 Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobr的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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