肿瘤易感基因101蛋白抗体Anti-Tsg101ESCRT I complex subunit TSG101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumo
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性能参数：

中文名称：肿瘤易感基因101蛋白抗体
英文名称：Anti-Tsg101
别名：ESCRT I complex subunit TSG101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumo
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth ａnd differentiation ａnd act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability ａnd cell cycle regulation. Mutations ａnd alternative splicing in this gene occur in high frequency in breast cancer ａnd suggest that defects occur during breast cancer tumorigenesis and/or progression. TSG101 also interacts with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses like HIV-1 p6, human spumavirus Gag, HTLV-1 Gag, as well as of Ebolavirus VP40.Subcellular Location : Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late endosome membrane; Peripheral membrane protein. Note=Mainly cytoplasmic. Membrane-associated when active ａnd soluble when inactive. Depending on the stage of the cell cycle, detected in the nucleus. Colocalized with CEP55 in the midbody during cytokinesis.Tissue Specificity : Heart, brain, placenta, lung, liver, skeletal, kidney ａnd pancreas.Similarity : Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.Contains 1 SB （steadiness box） domain.Contains 1 UEV （ubiquitin E2 variant） domain.

肿瘤易感基因101蛋白抗体的质量标准：

■其它名称：	ESCRT I complex subunit TSG101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumo
■交叉反应：	hu, mo, rat, cow, hrs, dog, Rb
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/细胞凋亡
■蛋白分子：	predicted molecular weight: 43kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	KLH conjugated synthetic peptide derived from human Tsg101 N-terminus
■亚型：	polyclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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由于化学产品的特殊性，恕不接受以下投诉：
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肿瘤易感基因101蛋白抗体Anti-Tsg101的相关产品目录：







1mg/1ml 肿瘤易感基因101蛋白抗体 Anti-Tsg101 ESCRT I complex subunit TSG101; TSG 10; TSG 101; TSG10; Tumor susceptibility gene 10; Tumo的来源为Rabbit，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

查询其它抗体目录请点击本公司化工仪器网链接：http://www.chem17.com/st233816/erlist_675408.html

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