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酪氨酸激酶A/B/C抗体 田源一抗
点击次数:155发布时间:2012/8/15 9:16:18
更新日期:2013/6/26 15:27:28
所 在 地:其它
产品型号:Anti-Trk A/B/C
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详细内容
酪氨酸激酶A/B/C抗体Anti-Trk A/B/CTrk A; TrkB; TrkC; Tyrosine Receptor Kinase A;Tyrosine Receptor Kinase B; Tyrosine Recepto
360TIYO.COM-上海田源公司
性能参数:
中文名称:酪氨酸激酶A/B/C抗体
英文名称:Anti-Trk A/B/C
别名:Trk A; TrkB; TrkC; Tyrosine Receptor Kinase A;Tyrosine Receptor Kinase B; Tyrosine Recepto
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:The Trk family of nerve growth factor receptors includes Trk A(also referfed to as Trk A gp140),Trk B and Trk C. The prototype member of this gene family, Trk A, encodes a 140 kDa cell surface receptor, gp140, the expression of which is restricted in vivo to neurons of the sensory spinal and cranial gangliaof neurocrest origin. Nerve growth factor (NGF) stimulates tyrosine phosphorylation of Trk gp 140 in neural cell lines and in embryonic dorsal root ganglia. By comparison, BDNF and to a lesser extent, NT-3, but not NGF, can induce tyrosine phophorylayion of Trk B gp 145. The third member of the Trk receptor family, Trk C incodes a 140 kDa protein, Trk C gp140, that is preferentially expressed in brain tissue and primarily functions as a receptor for NT-3.An additional component of the Trk receptor complex, NGFR p175, binds to neurotrophic factors with low affinity but is required for efficient signaling. NGFR p175 accelerates Trk activation and may recruit downstream dffector molecules to the ligand-bound receptor complex.神经生物学相关蛋白(Neurobiology)此抗体与Trk A、Trk B、Trk C 均有交叉反应。酪氨酸激酶A/B/C抗体的质量标准:
■其它名称: | Trk A; TrkB; TrkC; Tyrosine Receptor Kinase A;Tyrosine Receptor Kinase B; Tyrosine Recepto |
■交叉反应: | hu, rat, mo, chk |
■产品类型: | 一抗 |
■应用领域: | /细胞生物/免疫学/神经生物学/信号转导/细胞凋亡 |
■蛋白分子: | predicted molecular weight: 90kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Trk A/B/C |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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酪氨酸激酶A/B/C抗体Anti-Trk A/B/C的相关产品目录:
1mg/1ml 酪氨酸激酶A/B/C抗体 Anti-Trk A/B/C Trk A; TrkB; TrkC; Tyrosine Receptor Kinase A;Tyrosine Receptor Kinase B; Tyrosine Recepto的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
查询其它抗体目录请点击本公司化工仪器网链接:http://www.chem17.com/st233816/erlist_675408.html
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