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血栓调节蛋白抗体 田源一抗
点击次数:136发布时间:2012/8/15 9:16:34
更新日期:2013/6/26 15:27:20
所 在 地:其它
产品型号:Anti-Thrombomodulin/CD141
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详细内容
血栓调节蛋白抗体Anti-Thrombomodulin/CD141Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM.
360TIYO.COM-上海田源公司
性能参数:
中文名称:血栓调节蛋白抗体
英文名称:Anti-Thrombomodulin/CD141
别名:Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Thrombomodulin, TM is cell surface glycoprotein; plays an important role in the protein C anticoagulant pathway. It located in a vein, artery and capillary endothelial cells on the surface of plasma membrane protein. It is generally believed: TM vascular endothelial injury is an important parameter is the thrombin receptor, known in a variety of normal human tissues, can also be expressed in many tumors, TM may be similar to the E-cadherin,and is a lectin Like activity of a new class of members of the cell adhesion molecules.CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.血栓调节蛋白(thrombomodulin,TM)是一种分布于静脉、动脉和毛细血管内皮细胞表面的质膜蛋白。 一般认为:TM是血管内皮损伤的重要参数,也是凝血酶的受体,已知在人类多种正常组织中表达,亦可表达于许多肿瘤组织,TM可能类似于钙粘蛋白,是具有凝集素样活性的新一类细胞粘附分子的成员。血栓调节蛋白抗体的质量标准:
■其它名称: | Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM. |
■交叉反应: | hu, mo, rat, dog, Pig, cow |
■产品类型: | 一抗 |
■应用领域: | /心血管/细胞生物/神经生物学 |
■蛋白分子: | predicted molecular weight: 61kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Thrombomodulin |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IHC-P=1:100-500//IHC-F=1:100-500//Flow-Cyt=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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血栓调节蛋白抗体Anti-Thrombomodulin/CD141的相关产品目录:
1mg/1ml 血栓调节蛋白抗体 Anti-Thrombomodulin/CD141 Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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