肿瘤坏死因子-α单克隆抗体Anti-TNF-alpha（1F6）tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage
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性能参数：

中文名称：肿瘤坏死因子-α单克隆抗体
英文名称：Anti-TNF-alpha（1F6）
别名：tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage
包装号：G320
产地：中国大陆/进口产品
商标/品牌：Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商：田源试剂 TR、新试剂 NR
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产品详细描述

产品介绍：1F6Tumor Necrosis Factor Alpha （TNF alpha） is a protein secreted by lipopolysaccharide stimulated macrophages, ａnd causes tumor necrosis when injected into tumour bearing mice. TNF alpha is believed to mediate pathogenic shock ａnd tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS PAGE under non reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumour Necrosis Factor beta （lymphotoxin）, sharing the same receptors ａnd cellular actions. TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts ａnd other cell lines, activating polymorphonuclear neutrophils ａnd osteoclasts, ａnd induction of interleukin 1, prostaglandin E2 ａnd collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers ａnd AIDS Related Complex.肿瘤坏死因子是巨嗜细胞感染时或应激情况下自然产生的一种十分活跃的生物活性因子，可能与干扰素协同作用杀伤瘤细胞。

肿瘤坏死因子-α单克隆抗体的质量标准：

■其它名称：	tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage
■交叉反应：	hu
■产品类型：	一抗
■应用领域:	/肿瘤/细胞生物/免疫学/神经生物学/信号转导/细胞凋亡/生长因子和激素
■蛋白分子：	predicted molecular weight: 17/26kDa
■浓度值：	1mg/1ml
■物理性状：	Lyophilized or Liquid
■免疫原：	TNF alpha protein
■亚型：	monoclonal
■纯化方法：	affinity purified by Protein A
■保存液：	0.01M PBS, pH 7.4 with 10 mg/ml BSA ａnd 0.1% Sodium azide
■应用技术：	//WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500（石蜡切片需做抗原修复）/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user.
■保存环境：	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

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肿瘤坏死因子-α单克隆抗体Anti-TNF-alpha（1F6）的相关产品目录：







1mg/1ml 肿瘤坏死因子-α单克隆抗体 Anti-TNF-alpha（1F6） tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage的来源为Mouse，其相关产品：免疫组化常用试剂免疫印迹常用试剂各种标记二抗

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