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磷酸化马铃薯球蛋白(结节性硬化)抗体 田源一抗磷酸化抗体
点击次数:123发布时间:2012/8/15 9:18:37
更新日期:2013/6/26 15:26:41
所 在 地:其它
产品型号:Anti-Phospho-Tuberin/TSC2 (Ser1254)
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详细内容
磷酸化马铃薯球蛋白(结节性硬化)抗体Anti-Phospho-Tuberin/TSC2 (Ser1254)FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein.
360TIYO.COM-上海田源公司
性能参数:
中文名称:磷酸化马铃薯球蛋白(结节性硬化)抗体
英文名称:Anti-Phospho-Tuberin/TSC2 (Ser1254)
别名:FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein.
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.Tuberin 为180kD-220的蛋白产生于结节性硬化(TSC-2)位于染色体16的基因。结节性硬化为常染色体疾病已知为斑痣性错构瘤病其特征为广泛性发展呈良性生长,在许多组织与器官中描述为错构瘤。Tuberin被认为在GTPase活动性蛋白中起作用调节细胞内吞与作为肿瘤抑制子。Tuberin低水平广泛性表达在大多数组织中,而在皮层神经元、小脑浦肯野氏细胞、脊索运动神经元、胰岛B细胞、心肌、肾脏与皮肤的小血管中表达增加。磷酸化马铃薯球蛋白(结节性硬化)抗体的质量标准:
■其它名称: | FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein. |
■交叉反应: | hu, rat, mo |
■产品类型: | 一抗磷酸化抗体 |
■应用领域: | /肿瘤/心血管/细胞生物/免疫学/神经生物学/细胞凋亡 |
■蛋白分子: | predicted molecular weight: 200kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated Synthesised phosphopeptide derived from human Tuberin around the phosphorylation site of Ser1254 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //WB=1:100-500//ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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磷酸化马铃薯球蛋白(结节性硬化)抗体Anti-Phospho-Tuberin/TSC2 (Ser1254)的相关产品目录:
1mg/1ml 磷酸化马铃薯球蛋白(结节性硬化)抗体 Anti-Phospho-Tuberin/TSC2 (Ser1254) FLJ43106; LAM; TSC2; TSC2_HUMAN; TSC4; Tuberin; Tuberous sclerosis 2 protein.的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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