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L-型电压依赖型钙通道β抗体 田源一抗
点击次数:156发布时间:2012/8/15 9:19:43
更新日期:2013/6/26 15:26:21
所 在 地:其它
产品型号:Anti-CACNB2
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详细内容
L-型电压依赖型钙通道β抗体Anti-CACNB2Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Bet
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性能参数:
中文名称:L-型电压依赖型钙通道β抗体
英文名称:Anti-CACNB2
别名:Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Bet
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:CACNB2 is a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily, expressed in the CNS. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. It was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.电压依赖性钙通道(VDCC)是生物体内一大类钙通道蛋白,随着膜电位的改变而出现通道的开放、关闭和失活,调节细胞内Ca2+浓度,*终产生生物学效应.其亚型结构各异,VDCC β亚基具有调节其通道活性的作用,VDCC存在的普遍性决定了其作用的广泛性.在胰腺、心、脑、肾上腺、视网膜及神经等组织器官均有不同程度的分布.L-型电压依赖型钙通道β抗体的质量标准:
■其它名称: | Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Bet |
■交叉反应: | hu, mo, rat, hrs, Rb, dog, chk |
■产品类型: | 一抗 |
■应用领域: | /心血管/细胞生物/免疫学/神经生物学/通道蛋白 |
■蛋白分子: | predicted molecular weight: 72kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human CACNB2 |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //ELISA=1:500-1000//IP=1:20-100//IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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L-型电压依赖型钙通道β抗体Anti-CACNB2的相关产品目录:
1mg/1ml L-型电压依赖型钙通道β抗体 Anti-CACNB2 Voltage-dependent L-type calcium channel subunit beta-2; CAB2; Cacnb2; Cacnlb2; VDCC-L Bet的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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