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内脂素/前B细胞克隆增强因子-2(C端抗体) 田源一抗
点击次数:214发布时间:2012/8/15 9:19:50
更新日期:2013/6/26 15:26:21
所 在 地:其它
产品型号:Anti-PBEF (CT)
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详细内容
内脂素/前B细胞克隆增强因子-2(C端抗体)Anti-PBEF (CT)pre-B-cell colony enhancing factor 1 transcript variant 2; PBEF1 protein; 1110035O14Rik; A
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中文名称:内脂素/前B细胞克隆增强因子-2(C端抗体)
英文名称:Anti-PBEF (CT)
别名:pre-B-cell colony enhancing factor 1 transcript variant 2; PBEF1 protein; 1110035O14Rik; A
包装号:G320
产地:中国大陆/进口产品
商标/品牌:Santa、Abcam、MBL、BD、Cell Signaling Technology
供应商:田源试剂 TR、新试剂 NR
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产品详细描述
产品介绍:icotinamide phosphoribosyltransferase (NAmPRTase) (Nampt) (Pre-B cell-enhancing factor) (Pre-B-cell colony-enhancing factor 1) (Fisfatin) Catalyzes the condensation of nicotinamide with5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues. Subcellular Location is in Cytoplasm. Belongs to the NAPRTase family.Subcellular Location : Cytoplasm. Nucleus (rat, mouse).Tissue Specificity : Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.Similarity : Belongs to the NAPRTase family.Subunit : Homodimer.一种新的脂肪因子-visfatin (前B细胞克隆增强因子-2)是新近发现的主要由人和小鼠内脏脂肪组织分泌的一种脂肪细胞因子,其结构与pre-B细胞集落增强因子相似.它能够发挥类似胰岛素的作用,与Ⅱ型糖尿病相关联,降低血糖,促进糖摄取,可结合并活化胰岛素受体,激活胰岛素信号通路.内脏脂肪因子-Visfatin与肥胖密切相关并能够促进脂肪细胞的分化,还能促进血管平滑肌细胞成熟.Visfatin的表达受炎症反应因子和多种激素的调节.PBEF-1可能是联系机体糖脂代谢的重要分子,它的发现可为揭示糖尿病与肥胖的发生发展机制提供新的研究思路,为代谢综合征的治疗提供新方案.内脂素/前B细胞克隆增强因子-2(C端抗体)的质量标准:
■其它名称: | pre-B-cell colony enhancing factor 1 transcript variant 2; PBEF1 protein; 1110035O14Rik; A |
■交叉反应: | hu, mo, rat, MK, dog, pig, cow, chk |
■产品类型: | 一抗 |
■应用领域: | /神经生物学/糖尿病/内分泌病 |
■蛋白分子: | predicted molecular weight: 52kDa |
■浓度值: | 1mg/1ml |
■物理性状: | Lyophilized or Liquid |
■免疫原: | KLH conjugated synthetic peptide derived from human Visfatin-2 C-terminus |
■亚型: | polyclonal |
■纯化方法: | affinity purified by Protein A |
■保存液: | 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide |
■应用技术: | //IHC-P=1:100-500//IHC-F=1:100-500//IF=1:100-500(石蜡切片需做抗原修复)/not yet tested in other applications./optimal dilutions/concentrations should be determined by the end user. |
■保存环境: | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
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内脂素/前B细胞克隆增强因子-2(C端抗体)Anti-PBEF (CT)的相关产品目录:
1mg/1ml 内脂素/前B细胞克隆增强因子-2(C端抗体) Anti-PBEF (CT) pre-B-cell colony enhancing factor 1 transcript variant 2; PBEF1 protein; 1110035O14Rik; A的来源为Rabbit,其相关产品:免疫组化常用试剂免疫印迹常用试剂各种标记二抗
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