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厦门慧嘉生物专业销售CYT-335 GDF15 H Human Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec peprotech细胞因子特价。等生物试剂产品。实验为大，诚信经营，为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆（向客服人员索取原版说明书） http://www.biohj.com 欢迎广大老师来询！
GDF15 H Human
产品编号：CYT-335
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | GDF-15, MIC1, MIC-1, NAG-1, PDF, PLAB, PTGFB, Growth/differentiation factor 15, Placental bone morphogenetic protein, Placental TGF-beta, Macrophage inhibitory cytokine 1, Prostate differentiation factor, NSAID-activated gene 1 protein, NSAID-regulated gene 1 protein, NRG-1, GDF15. |
| Introduction | GDF15 is part of the TGF-Beta superfamily that is involved in regulating inflammatory ａnd apoptotic pathways in injured tissues ａnd throughout disease processes. GDF15 is most abundant in the liver. Its expression in liver can be considerably up-regulated in during injury of organs such as liver, kidney, heart ａnd lung. GDF-15 promotes proliferation or growth arrest ａnd differentiation due to differences in cellular differentiation. GDF15 prevents apoptosis in cerebellar granule neurons by activating Akt ａnd inhibiting endogenously active ERK. GDF15 is a novel autocrine/endocrine factor that antagonizes the hypertrophic response ａnd loss of ventricular performance. |
| Description | GDF15 H-variant Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated, Polypeptide chain containing 2x113 amino acids ａnd having a molecular mass of 24.8 kDa. The GDF15 H-variant is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearence | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Fomrulation | GDF15 H-variant is lyophilized without additives. |
| Solubility | It is recommended to reconstitute the lyophilized GDF15 H-variant in sterile 5mM AcOH （acetic Acid） at a concentration of 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized GDF15 H-variant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GDF15 should be stored at 4°C between 2-7 days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by （a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE. |
| Amino Acid Sequence | MARNGDHCPL GPGRCCRLHT VRASLEDLGW ADWVLSPREV QVTMCIGACP SQFRAANMHA QIKTSLHRLK PDTVPAPCCV PASYNPMVLI QKTDTGVSLQ TYDDLLAKDC HCI. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
