产品展示
PKA-264 GALK1 Human/重组人半乳糖激酶-1
点击次数：185发布时间：2012/7/18 12:10:58
更新日期：2024/10/16 15:58:55
所 在 地：美洲
产品型号：
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详细内容
GALK1 Human/重组人半乳糖激酶-1
产品编号：PKA-264
产品规格：5μg/20μg/1mg
Synonyms
Galactose kinase, GK1, GALK, EC 2.7.1.6, GALK1.
Introduction
GALK1 enzyme is needed in the first step of the galactose metabolism pathway.
（ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate）. GALK1 deficinecy lead galactosemia II which is an autosomal recessive deficiency known by congenital cataracts during infancy ａnd presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
Description
GALK1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 412 amino acids （1-392 a.a.） ａnd having a molecular mass of 44.4 kDa. The GALK1 is fused to 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
GALK1 Human solution containing 20mM Tris pH-8, & 10% glycerol.
Stability
GALK1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C.
Please prevent freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL.
Usage
ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
产品规格：5μg/20μg/1mg
Synonyms
Galactose kinase, GK1, GALK, EC 2.7.1.6, GALK1.
Introduction
GALK1 enzyme is needed in the first step of the galactose metabolism pathway.
（ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate）. GALK1 deficinecy lead galactosemia II which is an autosomal recessive deficiency known by congenital cataracts during infancy ａnd presenile cataracts in the adult population. The cataracts are secondary to accumulation of galactitol in the lenses.
Description
GALK1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 412 amino acids （1-392 a.a.） ａnd having a molecular mass of 44.4 kDa. The GALK1 is fused to 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
GALK1 Human solution containing 20mM Tris pH-8, & 10% glycerol.
Stability
GALK1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C.
Please prevent freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MAALRQPQVA ELLAEARRAF REEFGAEPEL AVSAPGRVNL IGEHTDYNQG LVLPMALELM TVLVGSPRKD GLVSLLTTSE GADEPQRLQF PLPTAQRSLE PGTPRWANYV KGVIQYYPAA PLPGFSAVVV SSVPLGGGLS SSASLEVATY TFLQQLCPDS GTIAARAQVC QQAEHSFAGM PCGIMDQFIS LMGQKGHALL IDCRSLETSL VPLSDPKLAV LITNSNVRHS LASSEYPVRR RQCEEVARAL GKESLREVQL EELEAARDLV SKEGFRRARH VVGEIRRTAQ AAAALRRGDY RAFGRLMVES HRSLRDDYEV SCPELDQLVE AALAVPGVYG SRMTGGGFGG CTVTLLEASA APHAMRHIQE HYGGTATFYL SQAADGAKVL CL.
Usage
ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
