产品展示
ENZ-423 NFNB E.Coli/重组大肠杆菌二氢喋啶还原酶
点击次数：261发布时间：2012/7/18 12:16:48
更新日期：2024/10/16 15:58:55
所 在 地：美洲
产品型号：
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详细内容
NFNB E.Coli/重组大肠杆菌二氢喋啶还原酶
产品编号：ENZ-423
产品规格：5μg/20μg/1mg
Synonyms
DPRA, NFSB, NFSI, NTR.
Introduction
NFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrugs in antibody directed enzyme prodrug therapy. NFNB reduces nitrofurazone, quis ａnd anti-tumor agent CB1954 （5-（aziridin-1-yl）-2,4-dinitrobenzamide）. The reduction of CB1954 results in the generation of cytotoxic species.
Description
NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids （1-217 a.a.） ａnd having a molecular mass of 26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearence
Sterile filtered colorless solution.
Formulation
1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol.
Stability
NFNB Human although stable at 4C for 1 week, should be stored desiccated
below -18C. Please prevent freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF
NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV.
Usage
ProSpec＇＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
NFNB E.Coli/重组大肠杆菌二氢喋啶还原酶
产品规格：5μg/20μg/1mg
Synonyms
DPRA, NFSB, NFSI, NTR.
Introduction
NFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrugs in antibody directed enzyme prodrug therapy. NFNB reduces nitrofurazone, quis ａnd anti-tumor agent CB1954 （5-（aziridin-1-yl）-2,4-dinitrobenzamide）. The reduction of CB1954 results in the generation of cytotoxic species.
Description
NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids （1-217 a.a.） ａnd having a molecular mass of 26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearence
Sterile filtered colorless solution.
Formulation
1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol.
Stability
NFNB Human although stable at 4C for 1 week, should be stored desiccated
below -18C. Please prevent freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MDIISVALKR HSTKAFDASK KLTPEQAEQI KTLLQYSPSS TNSQPWHFIV ASTEEGKARV AKSAAGNYVF
NERKMLDASH VVVFCAKTAM DDVWLKLVVD QEDADGRFAT PEAKAANDKG RKFFADMHRK DLHDDAEWMA KQVYLNVGNF LLGVAALGLD AVPIEGFDAA ILDAEFGLKE KGYTSLVVVP VGHHSVEDFN ATLPKSRLPQ NITLTEV.
Usage
ProSpec＇＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
