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CHM-375 GRO-Alpha Rat Recombinant (CXCL1)/重组大鼠GRO-Alpha(CXCL1)

点击次数:174发布时间:2012/7/19 14:36:05

CHM-375 GRO-Alpha Rat Recombinant (CXCL1)/重组大鼠GRO-Alpha(CXCL1)

更新日期:2024/10/16 15:58:55

所 在 地:美洲

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简单介绍:厦门慧嘉生物长期专业销售CHM-375 GRO-Alpha Rat Recombinant (CXCL1)/重组大鼠GRO-Alpha(CXCL1) \Santa\Abcam\ Cst\jackson\Pierce\Sigma\Amresco\Qiagen\Cayman \abnova\millipore\invitrogen\merk\ebioscience\prospec\peprotech细胞因子特价专供

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GRO-Alpha Rat Recombinant (CXCL1)/重组大鼠GRO-Alpha(CXCL1)

产品编号:CHM-375
产品规格:5μg/25μg/1mg
 
 

Synonyms

Growth-regulated protein alpha, CXCL1, Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha(1-73), chemokine (C-X-C motif) ligand 1, GRO1, GROa, SCYB1, MGSA-a, MGSA alpha.

Introduction

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). It is secreted by human melanoma cells, has mitogenic properties and is implicated in melanoma pathogenesis. CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. This chemokine elicits its effects by signaling through the chemokine receptor CXCR2. The gene for CXCL1 is located on human chromosome 4 amongst genes for other CXC chemokines.

Description

CXCL1 Rat Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7.8 kDa.
The Rat CXCL1 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearence

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated (1mg/ml) solution in 20mM PB, pH 7.4, and 150mM NaCl.

Solubility

Lyophilized CXCL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CXCL1 should be stored at 4C between 2-7 days and for future use below -18C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.

Amino Acid Sequence

APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA
CLDPEAPMVQ KIVQKMLKGV PK.

Biological Activity

Determined by its ability to chemoattract rat neutrophils using a concentration range of 10-100ng/ml.

Usage

Prospec''s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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