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PRO-443 Thyroglobulin Human/人甲状腺球蛋白
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更新日期：2024/10/16 15:58:55
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厦门慧嘉生物专业销售PRO-443 Thyroglobulin Human/人甲状腺球蛋白 Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec peprotech细胞因子特价。等生物试剂产品。实验为大，诚信经营，为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆（向客服人员索取原版说明书） http://www.biohj.com 欢迎广大老师来询！
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Thyroglobulin Human/人甲状腺球蛋白
产品编号：PRO-443
产品规格：20μg/100μg/1mg
Synonyms Thyroglobulin, TGN, AITD3, TG. Introduction Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen.
Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. Description Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. Source Native, Isolated from human thyroid glands. Formulation Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°Cfor longer periods of time.
Avoid multiple freeze-thaw cycles. Immunological functions 1. Binds to IgG-type human auto-antibodies.
2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes.
3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. Coating concentration 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）.
Suitable for biotinylation ａnd iodination. Purity Greater than 95% as determined by SDS-PAGE. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
产品规格：20μg/100μg/1mg
| Synonyms | Thyroglobulin, TGN, AITD3, TG. |
| Introduction | Thyroglobulin （TG） represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. TG is a large globular dimeric glycoprotein with a total molecular weight of 660 kDa, which occupies a key precursor role in the biosynthesis of the thyroid hormones. Approximately 75% of the total protein content of the thyroid follicle consists of TG. The thyroid gland uses the Thyroglobulin in order to produce the thyroid hormones thyroxine （T4） ａnd triiodothyronine （T3）. Thyroglobulin is produced by the thyroid epithelial cells （thyrocytes） which form spherical follicles. Thyroglobulin is subsequently secreted ａnd stored in the follicular lumen. Patients with Hashimoto＇s thyroiditis or Graves＇ disease, frequently develop antibodies against Thyroglobulin. Tg-specific antibodies help in the diagnosis of the above diseases, however they also may be present in apparently healthy euthyroid individuals. Blood Thyroglobulin levels can be used as a tumor marker for certain kinds of thyroid cancer, ａnd the may also be elevated in cases of Graves＇ disease. |
| Description | Human Thyroglobulin is a glycosylated, polypeptide chain having a total molecular mass of 662 kDa. |
| Source | Native, Isolated from human thyroid glands. |
| Formulation | Human Thyroglobulin is supplied in 16mM HEPES buffer pH-7.6, 240mM sodium chloride, ａnd 20% glycerol. |
| Storage Conditions | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°Cfor longer periods of time. Avoid multiple freeze-thaw cycles. |
| Immunological functions | 1. Binds to IgG-type human auto-antibodies. 2. Auto-antibodies to thyroglobulin recognize conformation-dependent epitopes. 3. Standard ELISA test （checker-board analysis of positive/negative sera panels, including 1st international reference serum NIBSC 65/93）. |
| Coating concentration | 0.7-1 μg/ml （depending on the type of ELISA plate ａnd coating buffer）. Suitable for biotinylation ａnd iodination. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
