您的位置:易推广 > 生物试剂/抗体/细胞 > 生化试剂 > 氨基酸 > 厦门慧嘉生物科技有限公司 > 产品展示 > 细胞因子 > PROSPEC > PRO-312 Tissue factor Human/重组人凝结因子III

产品展示

PRO-312 Tissue factor Human/重组人凝结因子III

点击次数:188发布时间:2012/7/24 16:13:36

PRO-312 Tissue factor Human/重组人凝结因子III

更新日期:2024/10/16 15:58:55

所 在 地:美洲

产品型号:

简单介绍:厦门慧嘉生物长期专业销售PRO-312 Tissue factor Human/重组人凝结因子III\Santa\Abcam\ Cst\jackson\Pierce\Sigma\Amresco\Qiagen\Cayman \abnova\millipore\invitrogen\merk\ebioscience\prospec\peprotech细胞因子特价专供

优质供应

详细内容

厦门慧嘉生物专业销售PRO-312 Tissue factor Human/重组人凝结因子III   Santa  Abcam  Cst   jackson    Pierce  Sigma    Amresco   Qiagen     Cayman    abnova    millipore   invitrogen  merk     ebioscience    prospec    peprotech细胞因子特价。等生物试剂产品。实验为大,诚信经营,为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆(向客服人员索取原版说明书) http://www.biohj.com 欢迎广大老师来询!
 
 

Tissue factor Human/重组人凝结因子III

产品编号:PRO-312
产品规格:2μg/10μg/1mg
 
 
Synonyms Tissue factor, Coagulation factor III, Thromboplastin, CD142, TF, F3, TFA.
Introduction Tissue factor is well-known as the main cellular initiator of blood coagulation. The Tissue factor gene encodes coagulation factor III which is a cell surface glycoprotein that enables cells to initiate the blood coagulation cascades, and functions as the high-affinity receptor for the coagulation factor VII. Following vessel injury, the Tissue Factor and Factor VIIa complex activates the coagulation protease cascade, which leads to fibrin deposition and activation of platelets. The ensuing complex presents a catalytic event, which is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Therefore, Tissue factor has a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. Tissue Factor can also be stimulated by the inflammatory mediators interleukin 1 and TNF, as well as by endotoxin, to appear on monocytes and vascular endothelial cells as a component of cellular immune response.
Tissue factor is the only one in the coagulation pathway for which a congenital deficiency has not been described. Certain levels of Tissue Factor are essential for the maintained viability and growth of endothelium and Tissue Factor-expressing tumor cells. Additionally, abnormal Tissue Factor expression inside the vasculature initiates life threatening thrombosis in various diseases, for example sepsis, atherosclerosis, and cancer. alternative spliced Tissue Factor expression advances tumor growth, and is linked to increased tumor cell proliferation and angiogenesis in pancreatic cancer.
Description Tissue factor Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 219 amino acids of the extracellular domain (33-251) having a molecular mass of 29.39 kDa and fused with a 4.5kDa amino-terminal hexahistidine tag.
The Tissue factor is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation Tissue factor protein is supplied in 22mM Tris.HCl pH8.0, 1mM EDTA and 50% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Purity Greater than 95.0% as determined by SDS-PAGE.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

联系我们

联系人:陈先生

点击查看联系方式

企业档案

  • 会员类型:免费会员
  • 工商认证: 【已认证】
  • 最后认证时间:
  • 法人:
  • 注册号:****
  • 企业类型:代理商
  • 注册资金:人民币万

script>
在线咨询

提交