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PRO-398 Parvalbumin Rat/重组大鼠细小清蛋白
点击次数：210发布时间：2012/8/1 15:51:52
更新日期：2024/10/16 15:58:55
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厦门慧嘉生物专业销售PRO-398 Parvalbumin Rat/重组大鼠细小清蛋白 ASSAY Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec peprotech细胞因子特价。等生物试剂产品。实验为大，诚信经营，为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆（向客服人员索取原版说明书） http://www.biohj.com 欢迎广大老师来询！
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Parvalbumin Rat/重组大鼠细小清蛋白
产品编号：PRO-398
产品规格：2μg/10μg/100μg
Synonyms Pvalb, Pva, PALB1, Parvalbumin. Introduction Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia.
Parvalbumin is identified as an allergen causing seafood allergy.
Pvalb may have evolved from an ancestral four domain calcium binding protein. Description Recombinant Rat Parvalbumin produced in E.Coli.
The Rat Parvalbumin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. Solubility It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 90% as determined by SDS-PAGE. Applications The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection.
For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
产品规格：2μg/10μg/100μg
| Synonyms | Pvalb, Pva, PALB1, Parvalbumin. |
| Introduction | Parvalbumin is calcium binding albumin protein, which binds two calcium ions. Parvalbumin has 3 EF hand motifs ａnd is structurally related to calmodulin ａnd troponin C. Pvalb is localized in fast-contracting muscles, where its levels are highest, in the brain ａnd some endocrine tissues. Parvalbumin is found in GABAergic interneurons in the nervous system, primarily expressed by chandelier ａnd basket cells in the cortex. Parvalbumin interneurons＇ connections are generally perisomatic （surrounding the cell body of neurons）. In the hippocampus, PV+ interneurons are subdivided into basket, axo-axonic, bistratified, ａnd oriens-lacunosum moleculare （O-LM） cells, each subtype targeting distinct domains of pyramidal cells. The majority of the Parvalbumin interneurons are fast-spiking, ａnd are thought to generate gamma waves recorded in EEG. Pvalb -expressing interneurons represent roughly 25% of GABA cells in the primate DLPFC. Decreased Parvalbumin ａnd GAD67 expression was found in PV+ GABAergic interneurons in schizophrenia. Parvalbumin is identified as an allergen causing seafood allergy. Pvalb may have evolved from an ancestral four domain calcium binding protein. |
| Description | Recombinant Rat Parvalbumin produced in E.Coli. The Rat Parvalbumin is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | The protein was lyophilized from a concentrated solution （1mg/ml） containing 10mM Tris-base, 70mM NaCl, 1mM EDTA ａnd 1mM b-mercaptoethanol, pH 7.4. |
| Solubility | It is recommended to reconstitute the lyophilized Parvalbumin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized Parvalbumin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Parvalbumin should be stored at 4°C between 2-7 days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Applications | The Parvalbumin can be used for immunoblots, absorption experiments in immunohistochemistry, radioimmunoassay ａnd intracellular injection. For fluid-phase adsorption in immunohistochemistry we suggest the following procedure: A- Dilute 1 μl of the monoclonal antibody 235 against parvalbumin in 5 ml of the usual buffer for immunohistochemistry （final dilution 1:5＇000）. B- Add 1μg of the Parvalbumin to 1ml of the diluted antibody solution ａnd mix well. C- Incubate for at least 6 hours in the cold. D- Apply to tissue-sections ａnd incubate for 3 days. D- Complete the immunohistochemical reaction as usual （biotinylated second antibody, ABC-complex, DAB）. As a result, the immunostaining should be strongly reduced or even completely prevented. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
