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PRO-526 MLH1 Human/重组人MutL同系物-1

点击次数:176发布时间:2012/8/8 16:37:48

PRO-526 MLH1 Human/重组人MutL同系物-1

更新日期:2024/10/16 15:58:55

所 在 地:美洲

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MLH1 Human/重组人MutL同系物-1

产品编号:PRO-526
产品规格:2μg/5μg/10μg
 
 
Synonyms DNA mismatch repair protein Mlh1, MutL protein homolog 1, MLH1, COCA2, FCC2, HNPCC, hMLH1, HNPCC2, MGC5172.
Introduction MLH1 is an 87kDa protein involved in mismatched nucleotides during DNA replication or repair process. Mutations in the human MLH1 (hMLH1) and hMLH2 genes contribute to the development of sporadic colorectal carcinoma and some other both hereditary and sporadic forms of human cancer.
MLH1 is identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). MLH1 is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic modifications in microsatellite sequences (RER+ phenotype) found in HNPCC.
Description MLH1 Human Recombinant (a.a. 557-756) expressed in E.coli, MLH1 is antibody reactive. The MLH1 is fused to a GST tag and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation The MLH1 at 100μg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications ? ELISA
? Inhibition Assays
? Western Blotting.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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