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Prospec PRO-690 Lamin-A/重组Lamin-A

点击次数:201发布时间:2012/8/8 17:08:30

Prospec PRO-690 Lamin-A/重组Lamin-A

更新日期:2024/10/16 15:58:55

所 在 地:美洲

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相关标签:Prospec PRO-690 Lamin-A 重组Lamin-A 

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Lamin-A/重组Lamin-A

产品编号:PRO-690
产品规格:2μg/10μg/0.1mg
 
 
Description Recombinant Lamin A produced in E.Coli is a single, non-glycosylated polypeptide chain containing 645 amino acids and having a molecular mass of 70 kDa. Lamin-A is a major component of the nuclear lamina, a dynamic meshwork located just under the nuclear envelope and it is encoded by lamin A/C gene (LMNA).
Lamin-A is synthesized as Prelamin A, a longer precursor that in vivo goes through a serial post-translational modifications that lead to mature Lamin A.
Diverse mutations in the Lamin A/C gene are associated with different diseases that are collectively called laminophaties, including Emery-Dreifuss muscular dystrophy, familiar partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation The Lamin-A Protein solution contains 10% Glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Purity Greater than 90.0% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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