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Prospec PRO-423 HPG-1 Human/重组人前列腺特异基因-1(HPG-1)

点击次数:202发布时间:2012/8/9 14:23:37

Prospec PRO-423 HPG-1 Human/重组人前列腺特异基因-1(HPG-1)

更新日期:2024/10/16 15:58:55

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HPG-1 Human/重组人前列腺特异基因-1(HPG-1)

产品编号:PRO-423
产品规格:2μg/10μg/1mg
 
 
Synonyms Human Prostate-Specific Gene-1, HPG-1, HPG1.
Introduction Human Prostate-Specific Gene-1 (HPG-1) product is a recently discovered membrane-anchored protein of approximately 15 kD. It was detected exclusively in the prostate (19 different tissues were tested).
Antisense-oligonicleotide inhibition of HPG-1 expression inhibited the growth of one prostate cancer cell line (LNCaP) significantly (86%). HPG-1 might be a novel diagnostic and/or therapeutic target.
Description Recombinant HPG-1 is a 16 kDa recombinant fusion protein consisting of 127 amino acid residues of the human PG-1 and 9 additional amino acid residues of the His-Tag (underlined).
MKHHHHHHHM IKKNLKKLGI EETYLNIIKA IYDRPTASIQ KTENLSTKTG TSQEYHLSPL WFYIVLEILA STIRQEKNLK DIHTEKEEVK LSLFADAMIL YLKKPNDSTR KLLELIKKIH SSCRIKINIH FAFCSQ.
Source Escherichia Coli.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation Sterile filtered and lyophilized from 0.5 mg/ml in 0.05M MES buffer pH 6.5.
Solubility Add 0.2 ml of dH2O and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited.
Stability Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time.
The lyophilized protein remains stable until the expiry date when stored at -20°C.
Purity Greater than 95% as determined by SDS-PAGE.
Specificity The amino acid sequence of the recombinant human PG-1 is 100% homologous to the amino acid sequence of the HPG-1.
Purification Method Ni-NTA affinity chromatography.
Applications Western blotting, ELISA.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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