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Prospec PRO-789 HEXIM1 Human/重组人环己烷Bis-乙酰胺诱导物1

点击次数:310发布时间:2012/8/9 14:29:47

Prospec PRO-789 HEXIM1 Human/重组人环己烷Bis-乙酰胺诱导物1

更新日期:2024/10/16 15:58:55

所 在 地:美洲

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简单介绍:厦门慧嘉生物长期专业销售Prospec PRO-789 HEXIM1 Human/重组人环己烷Bis-乙酰胺诱导物1\Santa\Abcam\ Cst\jackson\Pierce\Sigma\Amresco\Qiagen\Cayman \abnova\millipore\invitrogen\merk\ebioscience\prospec\peprotech细胞因子特价专供

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HEXIM1 Human/重组人环己烷Bis-乙酰胺诱导物1

产品编号:PRO-789
产品规格:2μg/10μg/1mg
 
 
 
 
Synonyms CLP1, EDG1, HIS1, MAQ1, Protein HEXIM1, Hexamethylene bis-acetamide-inducible protein 1, Estrogen down-regulated gene 1 protein, Cardiac lineage protein 1, Menage a quatre protein 1, FLJ13562.
Introduction HEXIM1 expression is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. HEXIM1 is a transcriptional regulator which acts as a universal RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex inhibits RNA polymerase II phosphorylation following transcriptional elongation. HEXIM1 regulates NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Description HEXIM1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 396 amino acids (1-359a.a.) and having a molecular mass of 44.8 kDa. HEXIM1 is fused to a 37 amino acid His-Tag at N-Terminus and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation HEXIM1 solution containing 20mM Tris pH-8, 0.1M NaCl and 10% glycerol.
Stability HEXIM1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Amino acid sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKFDEKQS LRASRIRAEM FAKGQPVAPY NTTQFLMDDH DQEEPDLKTG LYSKRAAAKS DDTSDDDFME EGGEEDGGSD GMGGDGSEFL QRDFSETYER YHTESLQNMS KQElikeYLE LEKCLSRMED ENNRLRLESK RLGGDDARVR ELELELDRLR AENLQLLTEN ELHRQQERAP LSKFGD.
Purity Greater than 90% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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