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Prospec PRO-505 FOS-B Human/重组人FOS-B

点击次数:274发布时间:2012/8/9 14:51:56

Prospec PRO-505 FOS-B Human/重组人FOS-B

更新日期:2024/10/16 15:58:55

所 在 地:美洲

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FOS-B Human/重组人FOS-B

产品编号:PRO-505
产品规格:2μg/5μg/10μg
 
 
 
Synonyms Protein fosB, G0/G1 switch regulatory protein 3, FOSB, G0S3, AP-1, GOS3, GOSB, MGC42291, DKFZp686C0818, FOS-B.
Introduction Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos- B include Fra-1 and Fra-2 genes. The 4 members of Fos gene family are: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins which can dimerize with proteins of the JUN family, thus forming the transcription factor complex AP-1. The FOS proteins act as regulators of cell proliferation, differentiation, and transformation. alternatively spliced transcript variants encoding different isoforms exist for Fos B.
Description FOS-B Human Recombinant (a.a. 113-151) expressed in E.coli, shows a 32 kDa SDS-PAGE (Including GST).
The FOS-B is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation FOS-B in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles.
Applications ? ELISA
? Inhibition Assays
? Western Blotting.
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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