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Prospec PRO-733 FADD Human/重组人Fas相关死亡结构域
点击次数：208发布时间：2012/8/9 16:04:15
更新日期：2024/10/16 15:58:55
所 在 地：美洲
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厦门慧嘉生物专业销售Prospec PRO-733 FADD Human/重组人Fas相关死亡结构域 ASSAY ImmunoWay Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec peprotech细胞因子特价。等生物试剂产品。实验为大，诚信经营，为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆（向客服人员索取原版说明书） http://www.biohj.com 欢迎广大老师来询！
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
Synonyms GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. Introduction FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. Description FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa.
FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Avoid multiple freeze-thaw cycles. Purity Greater than 95.0% as determined by SDS-PAGE. Amino Acid Sequence MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
FADD Human/重组人Fas相关死亡结构域
产品编号：PRO-733
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | GIG3, MORT1, MGC8528, FADD, Fas （TNFRSF6）-associated via death domain, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3 protein. |
| Introduction | FADD is an adaptor protein that cooperates with a variety of cell surface receptors ａnd mediates cell apoptotic signals. Using its C-terminal death domain, FADD is recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, ａnd TNFSF10/TRAIL-receptor, ａnd consequently it take parts in the death signaling initiated by these receptors. FADD interaction with the receptors reviels the N-terminal effector domain of, which allows it to recruit caspase-8, ａnd thus initiate the cysteine protease cascade. Knockout studies in mice furthermore propose the significance of FADD in premature T cell development. FADD plays a role in survival/proliferation ａnd cell cycle development. FADD also takes part in cellular sublocalization, protein phosphorylation, ａnd inhibitory molecules. |
| Description | FADD produced in E.Coli is a single, non-glycosylated polypeptide chain containing 244 amino acids （1-208 a.a.） ａnd having a molecular mass of 27.4 kDa. FADD is fused to 36 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | The FADD protein solution contains 20mM Tris-HCl, pH-8, ａnd 10% glycerol. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence | MRGSHHHHHHGMASMTGGQQ MGRDLYDDDD KDRWGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
