产品展示
Prospec PRO-291 ESAT6/重组早期分泌靶结核分枝杆菌
点击次数：239发布时间：2012/8/10 17:07:06
更新日期：2024/10/16 15:59:07
所 在 地：美洲
产品型号：
优质供应
详细内容
厦门慧嘉生物专业销售Prospec PRO-291 ESAT6/重组早期分泌靶结核分枝杆菌ASSAY ImmunoWay Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec peprotech细胞因子特价。等生物试剂产品。实验为大，诚信经营，为客户提供“质量的产品”和“质的服务"QQ: 1193953234 1048735792 或登陆（向客服人员索取原版说明书） http://www.biohj.com 欢迎广大老师来询！
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ESAT6/重组早期分泌靶结核分枝杆菌
产品编号：PRO-291
产品规格：10μg/50μg/1mg
Synonyms Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. Introduction Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients.
The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host.
This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide.
Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. Patent Rights The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. Description ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton.
The ESAT-6 contains 6 additional amino acid residues - His-Tag. Source Escherichia Coli. Physical Appearance Sterile Filtered White lyophilized （freeze-dried） powder. Formulation The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. Solubility It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. Stability Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below
-18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles. Purity Greater than 95.0% as determined by（a） Analysis by RP-HPLC.
（b） Analysis by SDS-PAGE. Amino Acid Composition AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
产品规格：10μg/50μg/1mg
| Synonyms | Early Secretory Target Mycobacterium Tuberculosis, ESAT-6. |
| Introduction | Mycobacterium antigen ESAT-6 has been isolated from low molecular weight fractions of the shot-term-culture filtrate （ST-CF） ａnd it can easily be detected in tuberculosis patients. The export of ESAT-6 which is a potent T-cell antigen, ａnd related proteins requires a dedicated secretory apparatus that is encoded by a group of genes, several of which also code for proteins that are recognized strongly by T cells. The ESAT-6 systems can consequently be considered as immunogenicity islands ａnd there is mounting evidence that the equivalent genes are subject to selective pressure imposed by the immune system of the host. This antigen includes many epitopes detectable in the serum of most patients with tuberculosis （more than 90%）. By the attempts to obtain the vaccine on the basis of ESAT-6 it was demonstrated that the optimization of adjuvant is very important when using the combination of dioctadecylammonium bromide ａnd monophosphoryllipide. Recently it was shown that ESAT-6 is very potential as diagnostic for differentiation between the mycobacterial infection ａnd BCG vaccination. The main topic in ESAT-6 using is in antibody production ａnd in test-systems for tuberculosis elaboration. |
| Patent Rights | The sale and/or commercial use of Recombinant ESAT-6 is prohibited in the United States of America （U.S.A）, Canada, Great Britain, Denmark, France, Greece, Italy, Germany, Spain, Ireland, Portugal, New Zealand ａnd Australia. |
| Description | ESAT-6 Recombinant produced in e.coli is a single, non-glycosylated, polypeptide having a total molecular mass of 11261.35 Dalton. The ESAT-6 contains 6 additional amino acid residues - His-Tag. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | The protein （1mg/ml） was lyophilized after from a sterile solution containing 50mM Tris-HCl, pH 8.0, 1mM EDTA ａnd 1mM DTT. |
| Solubility | It is recommended to reconstitute the lyophilized ESAT-6 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized ESAT-6 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ESAT-6 should be stored at 4°C between 2-7 days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE. |
| Amino Acid Composition | AEQQWNFAGIEAAASAIQGNVTSIHSLLDEGKQSLTKLAAAWGGSG SEAYQGVQQKWDATATELNNALQNLARTISEAGQAMASTEGNVTGMF AKLAAALEHHHHHH. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
