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A7190 p70 S6 Kinase （Phospho-Thr421） Antibody
| Reactivity | Applications | MW. | Source |
| H, M, R | WB IHC ELISA | 59 kDa | Rabbit |
Note: The product is for research use only, not for use in diagnostic or therapeutic procedures.
| Product Name | p70 S6 Kinase （Phospho-Thr421） Antibody |
| Synonyms | Ribosomal protein S6 kinase I; S6K; S6K1; 70 kDa ribosomal protein S6 kinase 1; p70 S6 kinase alpha; p70（S6K）-alpha; p70-S6K; P70S6K; p70-alpha |
| Immunogen | The antiserum was produced against synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Thr421. |
| Immunogen Region | C-terminal |
| Clonality | Polyclonal |
| Modification sites | H:T444 M:T444 R:T444 |
| Application dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000 |
| Specificity | p70 S6 Kinase （Phospho-Thr421） Antibody detects endogenous levels of p70 S6 Kinase only when phosphorylated at threonine421. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation. |
| Physical Form | Rabbit IgG in phosphate buffered saline （without Mg2+ ａnd Ca2+）, pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
| Concentration | 1 mg/ml |
| Storage/Stability | Store at -20℃/1 year |
| NCBI Gene Symbol | RPS6KB1 | ||||||||
| Database Links |
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| Application images |  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using p70 S6 Kinase （Phospho-Thr421） Antibody. The picture on the right is treated with the synthesized peptide.  Western blot analysis of extracts from NIH-3T3 cells treated with EGF 200ng/ml 30＇, using p70 S6 Kinase （Phospho-Thr421） Antibody. The lane on the left is treated with the synthesized peptide. |
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