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| Reactivity | Applications | MW. | Source |
| H, M, R | WB IHC ELISA | 137 kDa | Rabbit |
Note: The product is for research use only, not for use in diagnostic or therapeutic procedures.
| Product Name | HER2 （Phospho-Tyr1248） Antibody |
| Synonyms | C-erbB-2; Epidermal growth factor receptor-related protein; ErbB2; HER2; kinase ErbB2; MLN 19; NEU; NEU proto-oncogene; NGL; p185erbB2; Receptor protein-tyrosine kinase erbB-2; Receptor protein-tyrosine kinase erbB-2 precursor; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog （avian） |
| Immunogen | The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Tyr1248. |
| Immunogen Region | C-terminal |
| Clonality | Polyclonal |
| Modification sites | H:Y1248 M:Y1249 R:Y1250 |
| Application dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000 |
| Specificity | HER2 （Phospho-Tyr1248） Antibody detects endogenous levels of HER2 only when phosphorylated at tyrosine1248. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation. |
| Physical Form | Rabbit IgG in phosphate buffered saline （without Mg2+ ａnd Ca2+）, pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
| Concentration | 1 mg/ml |
| Storage/Stability | Store at -20℃/1 year |
| NCBI Gene Symbol | ERBB2 | ||||||||
| Database Links |
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| Application images |  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HER2 （Phospho-Tyr1248） Antibody. The picture on the right is treated with the synthesized peptide.  Western blot analysis of extracts from HepG2 cells treated with PMA 125ng/ml 30＇, using HER2 （Phospho-Tyr1248） Antibody. The lane on the right is treated with the synthesized peptide. |
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