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重组人RAB2A/RAB2A Human
重组人RAB2A/RAB2A Human
产品编号：PRO-244
产品规格：5ug/20ug/1mg
产品规格：5ug/20ug/1mg
| Catalogue Number | PRO-244 |
| Synonyms | Ras-related protein Rab-2A, RAB2A, RAB2. |
| Introduction | Ras-related protein Rab-2A （RAB2A）is a member of the small GTPase superfamily. RAB protein family members are nontransforming monomeric GTP-binding proteins of the Ras superfamily, which contain four highly conserved regions involved in GTP binding ａnd hydrolysis. In addition, RAB proteins are a fundamental part of endocytic pathways. RAB2A ａnd RAB2B are essential for protein transport from the ER to the Golgi; RAB2A is lipid-anchored to the ER-Golgi intermediate compartment membrane whereas RAB2B is lipid anchored to the cytoplasmic side of the cell membrane. RAB2A also interacts with GOLGA2. |
| Description | RAB2A produced in E.Coli is a single, non-glycosylated polypeptide chain containing 236 amino acids （1-212 a.a） ａnd having a molecular mass of 26.1kDa. RAB2A is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | RAB2A protein solution （0.5mg/ml） containing 20mM Tris-HCl buffer （pH 8.0）, 1mM DTT, 20% glycerol ａnd 100mM NaCl. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH SGSHMAYAYL FKYIIIGDTG VGKSCLLLQF TDKRFQPVHD LTIGVEFGAR MITIDGKQIK LQIWDTAGQE SFRSITRSYY RGAAGALLVY DITRRDTFNH LTTWLEDARQ HSNSNMVIML IGNKSDLESR REVKKEEGEA FAREHGLIFM ETSAKTASNV EEAFINTAKE IYEKIQEGVF DINNEANGIK IGPQHAATNA THAGNQGGQQ AGGGCC. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
