产品展示
S100A1 重组小鼠S100钙结合蛋白A1/S100A1 Mouse
点击次数:150发布时间:2012/9/12 22:25:17
更新日期:2024/10/16 16:00:19
所 在 地:美洲
产品型号:
优质供应
详细内容
重组小鼠S100钙结合蛋白A1/S100A1 Mouse
产品规格:5ug/20ug/1mg
Catalogue Number | PRO-237 |
Synonyms | Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100a1, S100, S100a, AI266795. |
Introduction | S100A1 is a member of the S100 family of calcium binding proteins with EF-hand type Ca+2 binding motive. S100A1 (Calcium Binding Protein A1) is involved in the activation of sarcoplasmatic calcium release and the regulation of intermediate filament polymerization. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of S100A1 has been implicated in cardiomyopathies. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21. |
Description | S100A1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (1-94 a.a) and having a molecular mass of 12.6kDa (molecular weight on SDS-PAGE will appear higher). |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered clear solution. |
Formulation | S100A1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl. |
Stability | S100A1 Mouse Recombinant although stable at 4°C for 1 week, should be stored below -18°C. |
Purity | Greater than 90.0% as determined by SDS-PAGE. |
Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MGSELESAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSGFLDVQK DADAVDKVMK ELDENGDGEV DFKEYVVLVA ALTVACNNFF WETS. |
Usage | Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |