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S100A1 重组小鼠S100钙结合蛋白A1/S100A1 Mouse

点击次数:150发布时间:2012/9/12 22:25:17

S100A1 重组小鼠S100钙结合蛋白A1/S100A1 Mouse

更新日期:2024/10/16 16:00:19

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简单介绍:S100A1 重组小鼠S100钙结合蛋白A1/S100A1 Mouse

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S100A1 重组小鼠S100钙结合蛋白A1/S100A1 Mouse

重组小鼠S100钙结合蛋白A1/S100A1 Mouse

产品编号:PRO-237 
产品规格:5ug/20ug/1mg
Catalogue Number PRO-237
Synonyms

Protein S100-A1, S-100 protein alpha chain, S-100 protein subunit alpha, S100 calcium-binding protein A1, S100a1, S100, S100a, AI266795.

Introduction S100A1 is a member of the S100 family of calcium binding proteins with EF-hand type Ca+2 binding motive. S100A1 (Calcium Binding Protein A1) is involved in the activation of sarcoplasmatic calcium release and the regulation of intermediate filament polymerization. S100A1 may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of S100A1 has been implicated in cardiomyopathies.
S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. There are at least 13 members in the S100 gene family, which are located as a cluster on chromosome 1q21.
Description

S100A1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (1-94 a.a) and having a molecular mass of 12.6kDa (molecular weight on SDS-PAGE will appear higher).
S100A1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source Escherichia Coli.
Physical Appearance Sterile Filtered clear solution.
Formulation

S100A1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 0.1M NaCl.

Stability

S100A1 Mouse Recombinant although stable at 4°C for 1 week, should be stored below -18°C. 
Please prevent freeze thaw cycles.

Purity Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSELESAME TLINVFHAHS GKEGDKYKLS KKELKDLLQT ELSGFLDVQK DADAVDKVMK ELDENGDGEV DFKEYVVLVA ALTVACNNFF WETS.

Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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