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MAPRE3 Human
产品编号：PRO-264
产品规格：5ug/20ug/1mg
产品规格：5ug/20ug/1mg
| Catalogue Number | PRO-264 |
| Synonyms | RP3, EB3, EBF3, End-binding protein 3, EBF3-S, APC binding protein. |
| Introduction | MAPRE3 is a microtubule related protein that cooperates with the colorectal adenomatous polyposis coli tumor suppressor protein ａnd takes a curtail part in regulating microtubule dynamics, cell polarity, ａnd chromosome stability. MAPRE3 protein is related to MAPRE1 ａnd also associates with the microtubule cytoskeleton. MAPRE3 is expressed mainly in the central nervous system ａnd specially associates with APCL, a homolog of the adenomatous polyposis coli tumor suppressor protein. |
| Description | MAPRE3 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 301 amino acids （1-281a.a.） ａnd having a molecular mass of 34.1kDa. MAPRE3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | The MAPRE3 protein solution （1mg/1ml） is formulated in 20mM Tris-HCl buffer （pH 8.0） 2mM DTT, 0.1M NaCl ａnd 10% glycerol. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
