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重组人转位蛋白/TSN Human
产品编号：PRO-271
产品规格：5ug/20ug/1mg
产品规格：5ug/20ug/1mg
| Catalogue Number | PRO-271 |
| Synonyms | Translin, TRSLN, BCLF-1, REHF-1, RCHF1, TBRBP, Recombination Hotspot-binding Protein, Recombination Hotspot ssociated factor. |
| Introduction | Translin is a DNA ａnd RNA binding protein that identifies specifically preserved target sequences at the breakpoint junction of chromosomal translocations. TSN forms a ring-shaped configuration, that is in charge of DNA binding, ａnd in addition has a leucine zipper motif, which is believed to assist TSN to form dimers. TSN exports specific mRNAs out of the nucleus, reinforced by its localization in both the nuclei ａnd cytoplasm of neurons, ａnd regulates their translation. |
| Description | TSN produced in E.Coli is a single, non-glycosylated polypeptide chain containing 228 amino acids （1-228a.a.） ａnd having a molecular mass of 26.1kDa. TSN is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | The TSN protein solution （1mg/1ml） is formulated in 20mM Tris-HCl buffer （pH 8.0） 1mM DTT, 100mM NaCl, ａnd 10% glycerol. |
| Amino Acid Sequence | MSVSEIFVEL QGFLAAEQDI REEIRKVVQS LEQTAREILT LLQGVHQGAG FQDIPKRCLK AREHFGTVKT HLTSLKTKFP AEQYYRFHEH WRFVLQRLVF LAAFVVYLET ETLVTREAVT EILGIEPDRE KGFHLDVEDY LSGVLILASE LSRLSVNSVT AGDYSRPLHI STFINELDSG FRLLNLKNDS LRKRYDGLKY DVKKVEEVVY DLSIRGFNKE TAAACVEK |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
