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SBDS Human
产品编号：PRO-272
产品规格：5ug/20ug/1mg
产品规格：5ug/20ug/1mg
| Catalogue Number | PRO-272 |
| Synonyms | SDS, SWDS, Shwachman-Bodian-Diamond syndrome, Ribosome Maturation protein SBDS. |
| Introduction | SBDS is part of an extremely preserved protein family which exists from archaea to vertebrates ａnd plants. SBDS protein functions in RNA metabolism ａnd has a role in the biogenesis of the 60S ribosomal subunit ａnd translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder produced by mutations in the SBDS gene. |
| Description | SBDS produced in E.Coli is a single, non-glycosylated polypeptide chain containing 270 amino acids （1-250a.a.） ａnd having a molecular mass of 30.9kDa. SBDS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | The SBDS protein solution （0.5mg/1ml） is formulated in 20mM Tris-HCl buffer （pH8.0） 2mM DTT, 50mM NaCl, 0.1mM EDTA, ａnd 20% glycerol. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MSIFTPTNQI RLTNVAVVRM KRAGKRFEIA CYKNKVVGWR SGVEKDLDEV LQTHSVFVNV SKGQVAKKED LISAFGTDDQ TEICKQILTK GEVQVSDKER HTQLEQMFRD IATIVADKCV NPETKRPYTV ILIERAMKDI HYSVKTNKST KQQALEVIKQ LKEKMKIERA HMRLRFILPV NEGKKLKEKL KPLIKVIESE DYGQQLEIVC LIDPGCFREI DELIKKETKG KGSLEVLNLK DVEEGDEKFE |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
