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牛凝血酶/Thrombin Bovine
产品编号：PRO-447
产品规格：50U/100U/250U
产品规格：50U/100U/250U
Catalogue NumberPRO-447IntroductionThrombin enzyme （Activated Factor IIa） is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein ａnd a serine protease （EC 3.4.21.5） that catalyzes many coagulation-related reactions. Thrombin triggers factor-XI, factor-V, Factor-XIII ａnd factor-VIII. Thrombin endorses platelet activation, using activation of protease-activated receptors on the platelet. As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site （Leu-Val-Pro-Arg-Gly-Ser） is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine ａnd Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity.SourceBovine Blood.Physical AppearanceSterile Filtered White lyophilized （freeze-dried） powder.FormulationLyophilized freeze dry powder formulated with Tris buffer ａnd sodium chloride.SolubilityIt is recommended to reconstitute the lyophilized Thrombin in sterile 18MΩ-cm H2O.StabilityLyophilized Thrombin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IPF1 should be stored at 4°C between 2-7 days ａnd for future use below -18°C.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.Biological Activity2000 NIH U/mg.UsageProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）.
Please prevent freeze-thaw cycles.Biological Activity2000 NIH U/mg.UsageProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
