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重组人琥珀酸脱氢酶复合因子2/SDHAF2 Human
点击次数：121发布时间：2012/9/13 14:25:16
更新日期：2024/10/16 16:00:19
所 在 地：美洲
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重组人琥珀酸脱氢酶复合因子2/SDHAF2 Human
产品编号：PRO-593
产品规格：5ug/20ug/1mg
产品规格：5ug/20ug/1mg
| Catalogue Number | PRO-593 |
| Synonyms | Succinate dehydrogenase assembly factor 2 mitochondrial, SDH assembly factor 2, Succinate dehydrogenase subunit 5, mitochondrial, hSDH5, SDHAF2, C11orf79, PGL2, SDH5. |
| Introduction | Succinate Dehydrogenase Complex Assembly Factor 2 （SDHAF2） is a mitochondrial protein required for the flavination of a succinate dehydrogenase complex subunit essential for activity of the complex. DHAF2 is necessary for insertion of FAD cofactor into SDHA, the catalytic subunit of succinate dehydrogenase （SDH）. SDH is involved in complex II of the mitochondrial electron transport chain ａnd is responsible for transferring electrons from succinate to ubiqui （coenzyme Q）. SDHAF2 gene defects are the cause of hereditary paragangliomas type 2 （PGL2）, otherwise known as familial non-chromaffin paragangliomas type 2. |
| Description | SDHAF2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 160 amino acids （30-166 a.a） ａnd having a molecular mass of 19kDa. SDHAF2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | SDHAF2 protein solution （0.5mg/ml） containing 20mM Tris-HCl buffer （pH 8.0）, 0.2M NaCl, 30% glycerol ａnd 1mM DTT. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Amino acid sequence | MGSSHHHHHH SSGLVPRGSH MGSSFRRFYR GDSPTDSQKD MIEIPLPPWQ ERTDESIETK RARLLYESRK RGMLENCILL SLFAKEHLQH MTEKQLNLYD RLINEPSNDW DIYYWATEAK PAPEIFENEV MALLRDFAKN KNKEQRLRAP DLEYLFEKPR. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
