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重组人增殖细胞核抗原,GST标签/PCNA Human, GST
点击次数：115发布时间：2012/9/13 14:38:21
更新日期：2024/10/16 16:00:19
所 在 地：美洲
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详细内容
重组人增殖细胞核抗原,GST标签/PCNA Human, GST
产品编号：PRO-741
产品规格：2μg/5μg/10μg
产品规格：2μg/5μg/10μg
| Catalogue Number | PRO-741 |
| Synonyms | Proliferating cell nuclear antigen, PCNA, Cyclin, MGC8367. |
| Introduction | PCNA is located in the nucleus ａnd is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer ａnd helps elevate the processivity of leading strand synthesis during DNA replication. In reaction to DNA damage, PCNA is ubiquitinated ａnd takes part in the RAD6-dependent DNA repair pathway. 2 transcript variants encoding the same protein have been found for PCNA gene. Pseudogenes of this PCNA gene have been described on chromosome 4 ａnd on the X chromosome. PCNA is expressed during late G1- phase, S-phase of mitosis ａnd persists until the end of the M-phase because of its long biological half-life. PCNA is induced by UV irradiation. |
| Description | PCNA full length Human Recombinant protein produced in E.Coli is a single, non-glycosylated polypeptide chain having a molecular mass of 62kDa which includes GST-tag fusion protein. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | The PCNA solution contains 50mM Tris-Acetate pH-7.5 & 1mM EDTA & 20% glycerol. |
| Stability | PCNA although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
