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GNLY Human/重组人粒溶蛋白
产品编号：PRO-852
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | LAG2, Lymphokine LAG-2, TLA519, NKG5, LAG2, D2S69E, Granulysin, T-cell activation protein 519, GNLY, D2S69E. |
| Introduction | GNLY is part of the SAPLIP family ａnd is located in the cytotoxic granules of T cells, which are discharged upon antigen stimulation. GNLY is localized in cytotoxic granules of cytotoxic T lymphocytes ａnd natural killer cells, ａnd it has antimicrobial activity against M. tuberculosis ａnd other organisms. GNLY is an antimicrobial protein that kills intracellular pathogens. GNLY is active against a wide range of microbes, including Gram-positive ａnd Gram-negative bacteria, fungi, ａnd parasites. Kills Mycobacterium tuberculosis. |
| Description | GNLY Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing double His Tag ａnd having a total molecular mass of 18.1 kDa. The GNLY is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | The Granulysin protein was lyophilized from a concentrated （1mg/ml） solution containing no additives. |
| Solubility | It is recommended to reconstitute the lyophilized Granulysin in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized Granulysin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Granulysin should be stored at 4°C between 2-7 days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by SDS-PAGE. |
| Amino acid sequence | The sequence of the first 25 N-terminal amino acids was determined ａnd was found to be MGSSHHHHHHSSGLVPRGSHMMEGL. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
