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PRO-504 Filaggrin Human/重组人聚角蛋白微丝蛋白
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Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
Synonyms Filaggrin, FLG, ATOD2. Introduction Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. Description Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）.
The Filaggrin is purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile Filtered clear solution. Formulation Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. Stability Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Please prevent freeze-thaw cycles. Applications ? ELISA
? Inhibition Assays
? Western Blotting. Usage Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Filaggrin Human/重组人聚角蛋白微丝蛋白
产品编号：PRO-504
产品规格：2μg/5μg/10μg
产品规格：2μg/5μg/10μg
| Synonyms | Filaggrin, FLG, ATOD2. |
| Introduction | Filaggrins are an important class of the intermediate filament-associated proteins which interact with keratin intermediate filaments （Ifs） of terminally differentiating mammalian epidermis. Filaggrins exhibit wide species variations. Filaggrin also appears to be a target molecule for rheumatoid arthritis-specific auto-antibodies in humans. Profilaggrin is a key protein component of the keratohyalin granules of mammalian epidermis. It is primarily expressed as a large polyprotein precursor which is later proteolytically processed into individual functional filaggrin molecules. Persons with truncation mutations in the filaggrin gene, are strongly predisposed to a severe form of dry skin, （ichthyosis vulgaris）, and/or eczema. It was shown that approximately 50% of all severe cases of eczema may have at least one mutated filaggrin gene. Truncation mutations R501X ａnd 2284del4 are the most widespread mutations in the caucasian population, with 7-10% of the caucasian population carrying at least one copy of these mutations. R501X ａnd 2284del4 are not usually found in non-caucasian individuals, nevertheless novel mutations （3321delA ａnd S2554X） have been found in Japanese populations that yield similar effects. |
| Description | Filaggrin Human Recombinant （a.a. 3838-4062） expressed in E.coli, shows a 53 kDa SDS-PAGE （Including GST）. The Filaggrin is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | Filaggrin in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. |
| Stability | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles. |
| Applications | ? ELISA ? Inhibition Assays ? Western Blotting. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
