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PRO-772 ENSA Human/重组人内磺肽Alpha
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ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
Synonyms ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. Introduction ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. Description ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. Source Escherichia Coli. Physical Appearance Sterile filtered colorless solution. Formulation The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. Purity Greater than 90.0% as determined by SDS-PAGE. Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. Usage ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ENSA Human/重组人内磺肽Alpha
产品编号：PRO-772
产品规格：5μg/25μg/1mg
产品规格：5μg/25μg/1mg
| Synonyms | ARPP-19e, Alpha endosulfine isoform 3, Alpha-endosulfine, ENSA, MGC4319, MGC8394, MGC78563. |
| Introduction | ENSA is an endogenous ligand for sulfonylurea receptor. ENSA reduces K（ATP） channel currents by inhibiting sulfonylurea from binding to the receptor ａnd thus stimulates insulin secretion. Endosulfine Alpha is part of a conserved cAMP-regulated phosphoprotein （ARPP） family. Endosulfine Alpha is an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. Endosulfine Alpha is an endogenous regulator of KATP channels. ENSA modulates insulin secretion through the interaction with KATP channel. ENSA is a candidate gene for type 2 diabetes. ENSA is expressed in a wide range of tissues including muscle, brain, ａnd endocrine tissues. |
| Description | ENSA Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids （1-121 a.a.） ａnd having a molecular wieght of 15.5kDa. The ENSA is fused to a 20 amino acid His-Tag at N-terminus ａnd purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile filtered colorless solution. |
| Formulation | The Endosulfine Alpha protein solution contains 20mM Tris, pH-8, 1mM DTT ａnd 10% glycerol. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Stability | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles. |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MSQKQEEENP AEETGEEKQD TQEKEGILPE RAEEAKLKAK YPSLGQKPGG SDFLMKRLQK GQKYFDSGDY NMAKAKMKNK QLPSAGPDKN LVTGDHIPTP QDLPQRKSSL VTSKLAGGQV E. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
