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RAB27A Human/重组人成员RAS原癌基因家族RAB27A

点击次数:152发布时间:2012/10/31 19:40:53

RAB27A Human/重组人成员RAS原癌基因家族RAB27A

更新日期:2024/10/16 16:00:43

所 在 地:美洲

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简单介绍:RAB27A Human/重组人成员RAS原癌基因家族RAB27A

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RAB27A Human/重组人成员RAS原癌基因家族RAB27A

产品编号:PRO-825 
产品规格:5μg/25μg/1mg

 

Synonyms GS2, RAM, RAB27, GS2, HsT18676, MGC117246, RAB27A, member RAS oncogene family.
Introduction RAB27A is part of the small GTPase superfamily, Rab family. RAB27A is membrane-bound and participates in protein transport and small GTPase mediated signal transduction. Mutations in this RAB27A are associated with Griscelli syndrome type 2. RAB27A is involved in cytotoxic granule exocytosis in lymphocytes.RAB27A is necessary for both granule maturation and granule docking and priming at the immunologic synapse.
Description RAB27A Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 241 amino acids (1-221a.a.) and having a molecular mass of 27 kDa. RAB27A protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
Source Escherichia Coli.
Physical Appearance Sterile filtered colorless solution.
Formulation RAB27A Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, & 20% glycerol.
Stability RAB27A Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino acid sequence MGSSHHHHHH SSGLVPRGSH MSDGDYDYLI KFLALGDSGV GKTSVLYQYT DGKFNSKFIT TVGIDFREKR VVYRASGPDG ATGRGQRIHL QLWDTAGQER FRSLTTAFFR DAMGFLLLFD LTNEQSFLNV RNWISQLQMH AYCENPDIVL CGNKSDLEDQ RVVKEEEAIA LAEKYGIPYF ETSAANGTNI SQAIEMLLDL IMKRMERCVD KSWIPEGVVR SNGHASTDQL SEEKEKGACG C.
Purity Greater than 90% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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