产品展示
HSPB8 Human/重组人热休克蛋白8-22kDa
点击次数：218发布时间：2012/10/31 19:55:01
更新日期：2024/10/16 16:00:43
所 在 地：美洲
产品型号：
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详细内容
HSPB8 Human/重组人热休克蛋白8-22kDa
产品编号：HSP-022
产品规格：2μg/10μg/100μg
产品规格：2μg/10μg/100μg
| Synonyms | HSPB8, H11, HMN2, CMT2L, DHMN2, E2IG1, HMN2A, HSP22, Heat shock protein beta-8, Alpha-crystallin C chain, Small stress protein-like protein HSP22, E2-induced gene 1 protein, Protein kinase H11, CRYAC. |
| Introduction | HSPB8 displays temperature-dependent chaperone activity. HSPB8 acts as a mn（2+）-dependent serine-threonine- specific protein kinase. we are not convinced that this is its true role. Defects in HSPB8 are a cause of distal hereditary motor neuropathy type ii （DHMN2） also known as distal spinal muscular atrophy （DSMA） ａnd spinal muscular atrophy of the charcot-marie-tooth type. it is an autosomal dominant disorder of lower motor neurons characterized by distal muscle weakness. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | The HSPB8 protein was lyophilized from a concentrated （1mg/ml） solution containing 20mM Tris-acetate, pH-7.6, 10mM NaCl, 0.1mM EDTA, 0.1mM PMSF, 15mM ?-ME. |
| Solubility | It is recommended to reconstitute the lyophilized HSPB8 in sterile 18M?-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
| Stability | Lyophilized HSPB8 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HSPB8 should be stored at 4°C between 2-7 days ａnd for future use below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Purity | Greater than 95.0% as determined by SDS-PAGE. |
| Immunological Activity | Immunoreactivity is confirmed by reaction with monoclonal mouse antibodies against HSPB8. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
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