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FABP5 Human/重组人脂肪酸结合蛋白-5
点击次数：162发布时间：2012/11/1 18:26:22
更新日期：2024/10/16 16:00:43
所 在 地：美洲
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FABP5 Human/重组人脂肪酸结合蛋白-5
产品编号：PRO-417
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | Fatty acid-binding protein epidermal, E-FABP, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, PA-FABP, FABP5, EFABP, PAFABP. |
| Introduction | Human Fatty Epidermal Acid Binding Protein FABP also called FABP-5 is a 15 kD member of the intracellular fatty acid binding protein （FABP） family, which is known for the ability to bind fatty acids ａnd related compounds （ bile acids or retinoids）. In an internal cavity. The fatty acid binding proteins aP2 （fatty acid binding protein [FABP]-4） ａnd mal1 （EFABP） are closely related ａnd both are expressed in adipocytes. Absence of EFABP/mal1 resulted in increased systemic insulin sensitivity in two models of obesity ａnd insulin resistance. Adipocytes isolated from mal1-deficient mice also exhibited enhanced insulin-stimulated glucose transport capacity. In contrast, mice expressing high levels of mal1 in adipose tissue display reduced systematic insulin activity. |
| Description | Recombinant Human Epidermal Fatty Acid Binding Protein （FABP-5） is a monodimeric, non-glycosylated, polypeptide chain containing 135 amino acids ａnd having a total molecular mass of 15200 Daltons. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered lyophilized （freeze-dried） powder. |
| Formulation | Sterile filtered ａnd lyophilized from 0.5 mg/ml in phosphate buffered saline. |
| Solubility | Add 0.2 ml of dH20 ａnd let the lyophilized pellet dissolve completely. |
| Stability | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid freeze-thaw cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. The lyophilized protein remains stable until the expiry date when stored at -20°C. |
| Purity | Greater than 90% as determined by SDS PAGE. |
| Specificity | The amino acid sequence of the recombinant human FABP5 is 100% homologous to the amino acid sequence of the human FABP-5. |
| Purification Method | Two-step procedure using size exclusion chromatography before ａnd after refolding. |
| Applications | Western blotting, ELISA. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
