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Cystatin C Rat/重组大鼠胱蛋白酶抑制剂C
点击次数：188发布时间：2012/11/1 18:36:03
更新日期：2024/10/16 16:00:43
所 在 地：美洲
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Cystatin C Rat/重组大鼠胱蛋白酶抑制剂C
产品编号：PRO-438
产品规格：2μg/10μg/1mg
产品规格：2μg/10μg/1mg
| Synonyms | Cystatin-C, Cystatin-3, CYSC, MGC105556. |
| Introduction | Cystatins are a superfamily of cysteine proteinase inhibitors found in both plants ａnd animals. They comprise a group of proteinase inhibitors, widely distributed in tissues ａnd body fluids, ａnd form tight complexes with cysteine proteases such as cathepsin B, H, L ａnd S. Cystatin C, a secreted molecule of this family, is of interest from biochemical, medicine ａnd evolutionary points of view. Cystatin C, with molecular weight of 13260 Da, is composed of 120 amino acids, lacks carbohydrate ａnd has two disulfide bridges located near the carboxyl terminus. Cystatin C is increased in patients with malignant diseases, ａnd is related to the insufficiency of renal function ａnd appears to be a better marker than creatinine. On the other hand, low levels of cystatin C involve cause the breakdown of the elastic laminae and, subsequently, the atherosclerosis ａnd abdominal aortic aneurysm. |
| Description | Total 134 AA, Mw: 14.93 kDa （calculated）. N-terminal His-tag （14AA）. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered White lyophilized （freeze-dried） powder. |
| Formulation | Filtered （0.4 micron） ａnd lyophilized from 0.5 mg/ml in 0.03M Acetate buffer, pH 4. |
| Solubility | Add 0.2 ml of 0.1M Acetate buffer pH4 ａnd let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 0.1mg/ml. In higher concentrations the solubility of this antigen is limited. |
| Stability | Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/ thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Minimum shelf life 2 years. |
| Amino Acid Sequence | MRGSHHHHHH GMASGTSRPP PRLLGAPQEA DASEEGVQRA LDFAVSEYNK GSNDAYHSRA IQVVRARKQLVAGINYYLDV EMGRTTCTKS QTNLTNCPFH DQPHLMRKAL CSFQIYSVPW KGTHTLTKSS. |
| Purity | Greater than 96% as determined by SDS-PAGE. |
| Applications | Western blotting. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
