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Cystatin A Human/重组人半胱氨酸蛋白酶抑制剂A
点击次数：143发布时间：2012/11/1 18:39:06
更新日期：2024/10/16 16:00:43
所 在 地：美洲
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Cystatin A Human/重组人半胱氨酸蛋白酶抑制剂A
产品编号：PRO-543
产品规格：2μg/5μg/10μg
产品规格：2μg/5μg/10μg
| Synonyms | Cystatin-A, Cystatin-AS, Stefin-A, CSTA, STF1, STFA. |
| Introduction | Cystatin-A is the intracellular inhibitor of cysteine proteinase cathepsin B （CatB） ａnd belongs to family 1 of the cystatin superfamily of inhibitor proteins. CSTA is a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain ａnd the cathepsins B, H, ａnd L. It has been proposed that extracellular CatB together with other classes of proteinases are all subjected to a cascade-like manner of activation. CatB ａnd its inhibitor Cystatin-A are involved in degradation of extracellular matrix proteins during tissue remodeling. CSTA is one of the precursor proteins of cornified cell envelope in keratinocytes ａnd plays a role in epidermal development ａnd maintenance. Cystatin-A has been reported to be found in high concentrations in epithelial cells, polymorphonuclear leukocytes ａnd lymphoid tissue. Stefins may be used as prognostic ａnd diagnostic tools for cancer. |
| Description | Cystatin-A Human Recombinant full length protein expressed in E.coli, shows a 37 kDa band on SDS-PAGE （including GST tag）. The Cystatin-A is purified by proprietary chromatographic techniques. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered clear solution. |
| Formulation | Cystatin-A in 50mM Tris-Acetate, pH7.5, 1mM EDTA ａnd 20% Glycerol. |
| Stability | Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles. |
| Applications | ? ELISA ? Inhibition Assays ? Western Blotting. |
| Usage | Prospec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
