产品展示
优质供应
详细内容
慧嘉生物您实验身边的好伙伴
为客户提供“品质的产品”和“*优质的服务”
AssayBiotech CUSABIO Immunoway Santa Abcam Cst jackson Pierce Sigma Amresco Qiagen Cayman abnova millipore invitrogen merk ebioscience prospec
欢迎广大客户咨询，另有大量宣传海报和小礼品赠送。
Q Q：
C1QBP Human/重组人补体1
产品编号：PRO-636
产品规格：5μg/25μg/1mg
产品规格：5μg/25μg/1mg
| Synonyms | p32, HABP1, gC1Qr, GC1QBP, SF2p32, gC1Q-R, Complement component 1 Q subcomponent-binding protein mitochondrial, Glycoprotein gC1qBP, C1qBP, GC1q-R protein, Hyaluronan-binding protein 1, Mitochondrial matrix protein p32, p33, C1QBP. |
| Introduction | C1QBP having the accession number of NP_001203 binds to the globular "heads" of c1q thus inhibiting c1 activation. C1QBP interacts with a wide range of ligands ａnd is implicated in cell signaling. C1QBP associates with C1r ａnd C1s in order to yield the first component of the serum complement system. C1QBP protein has been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. C1QBP is a new marker of tumor cells ａnd tumor-associated macrophages/myeloid cells in hypoxic/metabolically deprived areas of tumors. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, ａnd migration is mediated through ligation of both C1QBP ａnd cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit （MLTU） ａnd stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells. C1QBP binds with Hepacivirus core protein on CD8+ ａnd CD4+ positive t-cells ａnd inactivates lck ａnd akt. |
| Description | C1QBP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids ａnd having a molecular mass of 23.9 kDa. |
| Source | Escherichia Coli. |
| Physical Appearance | Sterile Filtered colorless solution. |
| Formulation | The C1QBP protein solution contains 20mM Tris-HCl pH7.5, 20% glycerol ａnd 1mM DTT. |
| Stability | C1QBP although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles. |
| Amino Acid Sequence | MLHTDGDKAF VDFLSDEIKE ERKIQKHKTL PKMSGGWELE LNGTEAKLVR KVAGEKITVT FNINNSIPPT FDGEEEPSQG QKVEEQEPEL TSTPNFVVEV IKNDDGKKAL VLDCHYPEDE VGQEDEAESD IFSIREVSFQ STGESEWKDT NYTLNTDSLD WALYDHLMDF LADRGVDNTF ADELVELSTA LEHQEYITFL EDLKSFVKSQ. |
| Purity | Greater than 95.0% as determined by（a） Analysis by RP-HPLC. （b） Analysis by SDS-PAGE. |
| Usage | ProSpec＇s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
